Evidence map›Paper›PMID 25419842›Full record

Observational studyPloS one2014

Observational study assessing demographic, economic and clinical factors associated with access and utilization of health care services of patients with multiple sclerosis under treatment with interferon beta-1b (EXTAVIA).

Georgios Hadjigeorgiou, Efthimios Dardiotis, Georgios Tsivgoulis, Triantafyllos Doskas, Damianos Petrou, Nikolaos Makris, Nikolaos Vlaikidis, Thomas Thomaidis, Athanasios Kyritsis, Nikolaos Fakas and 12 more

Erratum issuedOpen access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 13 institutions in 2 countries.

Georgios HadjigeorgiouNeurology Department at University Hospital of Larissa, Larissa, Greece.
Efthimios DardiotisNeurology Department at University Hospital of Larissa, Larissa, Greece.
Georgios TsivgoulisSecond Department of Neurology, University of Athens, School of Medicine, "Attikon" University Hospital, Athens, Greece.
Triantafyllos DoskasDepartment of Neurology, Athens Naval Hospital, Athens, Greece.
Damianos PetrouOutpatient Clinic at Vostanio General Hospital of Mytilini, Mytilini, Greece.
Nikolaos MakrisNeurology Department at Agios Andreas General University of Patra, Patra, Greece.
Nikolaos Vlaikidis3rd University Neurology Department at Papanikolaou University Hospital of Thessaloniki, Thessaloniki, Greece.
Thomas ThomaidisNeurology Department at Greek Red Cross Hospital, Athens, Greece.
Athanasios KyritsisUniversity Neurology Department at University Hospital of Ioannina, Ioannina, Greece.
Nikolaos FakasNeurology Department at 401 Military Hospital of Athens, Athens, Greece.
Xoulietta Treska2nd University Neurology Department at AHEPA General University Hospital of Thessaloniki, Thessaloniki, Greece.
Clementine KarageorgiouNeurology Department at Gennimatas General Hospital, Athens, Greece.
Stefania SotirliPrivate Practice, Athens, Greece.
Christos GiannoulisPrivate Practice, Athens, Greece.
Dimitra PapadimitriouNeurology Department at University Hospital of Larissa, Larissa, Greece.
Ioannis MylonasOutpatient Clinic at Interbalcan Medical Center, Thessaloniki, Greece.
Evaggelos KouremenosNeurology Department at 251 Air Force Hospital, Thessaloniki, Greece.
Georgios VlachosMedical Department, Novartis Hellas S.A.C.I., Athens, Greece.
Dimitrios GeorgiopoulosMedical Department, Novartis Hellas S.A.C.I., Athens, Greece.
Despoina MademtzoglouBECRO, Pharmaceutical Services, Athens, Greece; Department of Biomathematics, University of Thessaly School of Medicine, Larissa, Greece.
Michalis VikelisOutpatient Clinic at Interbalcan Medical Center, Thessaloniki, Greece; Medical Department, Novartis Hellas S.A.C.I., Athens, Greece.
Elias ZintzarasBECRO, Pharmaceutical Services, Athens, Greece; Department of Biomathematics, University of Thessaly School of Medicine, Larissa, Greece; The Institute for Clinical Research and Health Policy Studies, Tufts University School of Medicine, Boston, MA, United States of America.
University Hospital of Larissa · GRInterbalkan Medical Center · GR401 General Military Hospital of Athens · GRAgios Andreas Hospital · GRAHEPA University Hospital · GRAthens Naval & Veterans Hospital · GRG. Papanikolaou General Hospital · GRHellenic Air Force · GRHellenic Red Cross · GRNational and Kapodistrian University of Athens · GRTufts University · USUniversity Hospital of Ioannina · GRUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) results in an extensive use of the health care system, even within the first years of diagnosis. The effectiveness and accessibility of the health care system may affect patients' quality of life. The aim of the present study was to evaluate the health care resource use of MS patients under interferon beta-1b (EXTAVIA) treatment in Greece, the demographic or clinical factors that may affect this use and also patient satisfaction with the health care system. Structured interviews were conducted for data collection. In total, 204 patients (74.02% females, mean age (SD) 43.58 (11.42) years) were enrolled in the study. Analysis of the reported data revealed that during the previous year patients made extensive use of health services in particular neurologists (71.08% visited neurologists in public hospitals, 66.67% in private offices and 48.53% in insurance institutes) and physiotherapists. However, the majority of the patients (52.45%) chose as their treating doctor private practice neurologists, which may reflect accessibility barriers or low quality health services in the public health system. Patients seemed to be generally satisfied with the received health care, support and information on MS (84.81% were satisfied from the information provided to them). Patients' health status (as denoted by disease duration, disability status and hospitalization needs) and insurance institute were found to influence their visits to neurologists. Good adherence (up to 70.1%) to the study medication was reported. Patients' feedback on currently provided health services could direct these services towards the patients' expectations.

Indexed as

AdultAgedAnalysis of VarianceChi-Square DistributionFemaleHealth ServicesHealth Services AccessibilityHumansInterferon beta-1bMaleMiddle AgedMultiple SclerosisRetrospective StudiesSocioeconomic FactorsYoung AdultInterferon beta-1b

Identifiers

PMID25419842
PMCPMC4242657
OpenAlexW2071728776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.