Evidence map›Paper›PMID 25419513›Full record

ArticleGenomics data2014

Transcriptomic profiling of splenic B lymphomas spontaneously developed in B cell-specific TRAF3-deficient mice.

Ping Xie, Carissa R Moore, Mavis R Swerdel, Ronald P Hart

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genomics data, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ping XieDepartment of Cell Biology and Neuroscience, Rutgers University, Piscataway, New Jersey 08854 ; Member, Rutgers Cancer Institute of New Jersey.
Carissa R MooreDepartment of Cell Biology and Neuroscience, Rutgers University, Piscataway, New Jersey 08854.
Mavis R SwerdelDepartment of Cell Biology and Neuroscience, Rutgers University, Piscataway, New Jersey 08854 ; W.M. Keck Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854.
Ronald P HartDepartment of Cell Biology and Neuroscience, Rutgers University, Piscataway, New Jersey 08854 ; W.M. Keck Center for Collaborative Neuroscience, Rutgers University, Piscataway, New Jersey 08854 ; Member, Rutgers Cancer Institute of New Jersey.
Rutgers, The State University of New Jersey · US

Funding

TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Chang S Chan · 1997 to 2026
$94.5M
Molecular mechanisms of B cell malignant transformationR01CA158402 · NCI · RUTGERS, THE STATE UNIV OF N.J. · PI XIE, PING · 2012 to 2016
$1.6M
Genome-wide chromatin modification targeting by endogenous small RNAsRC1CA147187 · NCI · RUTGERS, THE STATE UNIV OF N.J. · PI HART, RONALD P, KELLIS, MANOLIS · 2010 to 2010
$996k
NCI NIH HHS P30 CA072720NCI NIH HHS R01 CA158402NCI NIH HHS RC1 CA147187
6 · The paper itself

Abstract

TRAF3, a critical regulator of B cell survival, was recently recognized as a tumor suppressor gene in B lymphocytes. Specific deletion of TRAF3 from B lymphocytes leads to spontaneous development of marginal zone lymphomas (MZL) or B1 lymphomas in mice. To identify novel oncogenes and tumor suppressive genes involved in malignant transformation of TRAF3-deficient B cells, we performed a microarray analysis to identify genes differentially expressed in TRAF3

Identifiers

PMID25419513
PMCPMC4236829
OpenAlexW2061992778

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.