Evidence map›Paper›PMID 25419387›Full record

ArticleInternational journal of clinical and experimental medicine2014

A retrospective study of the clinical differences of Uygur breast cancer patients compared to Han breast cancer patients in the Xinjiang region of China.

Meihui Shan, Xiaoli Wang, Gang Sun, Binlin Ma, Xuemei Yao, Alibiyati Ainy, Jing Ma, Chao Dong, Hongtao Li, Muzapar Abudukeremu

Abstract read
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In one paragraph

Article in International journal of clinical and experimental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
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7citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
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  3. Genetic risk between theHereditas · 2018
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  6. Therapeutic effects of cytoprotective agent on breast reconstruction after breast cancer surgery.International journal of clinical and experimental medicine · 2015
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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Meihui ShanDepartment of Breast and Neck, The Affiliated Tumor Hospital of Xinjiang Medical University 789 East Suzhou Street, Urumqi 830011, Xinjiang, China.
Xiaoli WangDepartment of Breast and Neck, The Affiliated Tumor Hospital of Xinjiang Medical University 789 East Suzhou Street, Urumqi 830011, Xinjiang, China.
Gang SunDepartment of Breast and Neck, The Affiliated Tumor Hospital of Xinjiang Medical University 789 East Suzhou Street, Urumqi 830011, Xinjiang, China.
Binlin MaDepartment of Breast and Neck, The Affiliated Tumor Hospital of Xinjiang Medical University 789 East Suzhou Street, Urumqi 830011, Xinjiang, China.
Xuemei YaoDepartment of Epidemiology and Health Statistics, Public Health College of Xinjiang Medical University 8 Medical University Road, Urumqi 830054, Xinjiang, China.
Alibiyati AinyDepartment of Breast and Neck, The Affiliated Tumor Hospital of Xinjiang Medical University 789 East Suzhou Street, Urumqi 830011, Xinjiang, China.
Jing MaDepartment of Breast and Neck, The Affiliated Tumor Hospital of Xinjiang Medical University 789 East Suzhou Street, Urumqi 830011, Xinjiang, China.
Chao DongDepartment of Breast and Neck, The Affiliated Tumor Hospital of Xinjiang Medical University 789 East Suzhou Street, Urumqi 830011, Xinjiang, China.
Hongtao LiDepartment of Breast and Neck, The Affiliated Tumor Hospital of Xinjiang Medical University 789 East Suzhou Street, Urumqi 830011, Xinjiang, China.
Muzapar AbudukeremuDepartment of Breast and Neck, The Affiliated Tumor Hospital of Xinjiang Medical University 789 East Suzhou Street, Urumqi 830011, Xinjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies support biological disparities of breast cancer among races/ethnicities. Uygur is a minority ethnic group in China with a genetic admixture of Caucasian and East Asian. The Han ethnic group makes up the majority of the Chinese population. We aim to study and compare the clinical differences and survival rate in these two ethnic groups in order to improve prophylaxis.

methodsA retrospective analysis of the medical records of 264 Uygur and 287 Han breast cancer patients including demographic data, clinical and pathological parameters, TNM status, Ki-67 and treatment information was collected. The patients were followed up at three month intervals for 2 years then every 6 months for 3 to 4 years postoperatively. Chi-square tests were performed to compare characteristics, and a log-rank test was used for ranked data. Overall survival and disease free survival were analyzed by Kaplan Meier tests.

resultsUygur was statistically different in terms of: marital status; occupation; body mass index; duration of breast feeding; period of complaint; pathological composition; size of primary tumor; number of metastatic and resected lymph nodes; pathological staging; expression of nm23; chemotherapy and radiotherapy. The 5-year overall survival rate of Uygur breast cancer patients was 89.2% compared to 91.7% in Han (P = 0.129). The disease free survival of Uygur breast cancer patients was 79.3% compared to 84.5% in Han (P = 0.040).

conclusionThe different characteristics of Uygur breast cancer patients compared to Han breast cancer patients and their lower survival rates indicate that management strategies should be implemented to improve patient outcome.

Indexed as

Breast neoplasmsChinaethnic groupspopulation characteristicssurvival

Identifiers

PMID25419387
PMCPMC4238510

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