Evidence map›Paper›PMID 25419041›Full record

ArticleJournal of carbohydrate chemistry2014

Glyco-modification of protein with

Valentinas Gruzdys, Hailong Zhang, Xue-Long Sun

Open access · greenAbstract read
In one paragraph

Article in Journal of carbohydrate chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Valentinas GruzdysDepartment of Chemistry, Chemical and Biomedical Engineering, and Center for Gene Regulation in Health and Disease (GRHD), Cleveland State University, 2121 Euclid Ave., Cleveland, OH 44115, USA.
Hailong ZhangDepartment of Chemistry, Chemical and Biomedical Engineering, and Center for Gene Regulation in Health and Disease (GRHD), Cleveland State University, 2121 Euclid Ave., Cleveland, OH 44115, USA.
Xue-Long SunDepartment of Chemistry, Chemical and Biomedical Engineering, and Center for Gene Regulation in Health and Disease (GRHD), Cleveland State University, 2121 Euclid Ave., Cleveland, OH 44115, USA.
Cleveland State University · US

Funding

Recombinant and Chemo-/Bio-Orthogonal Synthesis of Liposomal ThrombomodulinR01HL102604 · NHLBI · CLEVELAND STATE UNIVERSITY · PI SUN, XUE-LONG · 2010 to 2013
$1.2M
NHLBI NIH HHS R01 HL102604
6 · The paper itself

Abstract

Glycoengineering aimed at addition of carbohydrates to proteins is an attractive approach to alter pharmacokinetic properties of proteins such as enhancing stability and prolonging the duration of action. We report a novel protein glyco-modification of BSA and recombinant thrombomodulin with

Indexed as

Carbohydratecyanateglycopolymerisoureaproteinthrombomodulin

Identifiers

PMID25419041
PMCPMC4235998
OpenAlexW1983565842

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.