Evidence map›Paper›PMID 25419005›Full record

ArticleMikrochimica acta2014

Recent trends in SELEX technique and its application to food safety monitoring.

Jingjing Wu, Yingyue Zhu, Feng Xue, Zhanlong Mei, Li Yao, Xin Wang, Lei Zheng, Jian Liu, Guodong Liu, Chifang Peng and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mikrochimica acta, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Nucleic Acids Analysis.Science China. Chemistry · 2021
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Two-dimensional MoSMikrochimica acta · 2018
    Article
  18. Review
  19. Review
  20. Aptamer and its applications in neurodegenerative diseases.Cellular and molecular life sciences : CMLS · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jingjing Wu *School of Biotechnology and Food Engineering, Anhui Provincial Key Lab of Functional Materials & Devices, Hefei University of Technology, Hefei 230009, People's Republic of China.
Yingyue Zhu *School of Biotechnology and Food Engineering, Changshu Institute of Technology, Changshu 215500, People's Republic of China.
Feng Xue *School of Biotechnology and Food Engineering, Anhui Provincial Key Lab of Functional Materials & Devices, Hefei University of Technology, Hefei 230009, People's Republic of China.
Zhanlong MeiSchool of Biotechnology and Food Engineering, Anhui Provincial Key Lab of Functional Materials & Devices, Hefei University of Technology, Hefei 230009, People's Republic of China.
Li YaoSchool of Biotechnology and Food Engineering, Anhui Provincial Key Lab of Functional Materials & Devices, Hefei University of Technology, Hefei 230009, People's Republic of China.
Xin WangSchool of Biotechnology and Food Engineering, Anhui Provincial Key Lab of Functional Materials & Devices, Hefei University of Technology, Hefei 230009, People's Republic of China.
Lei ZhengSchool of Medical Engineering, Hefei University of Technology, Hefei 230009, People's Republic of China.
Jian LiuSchool of Biotechnology and Food Engineering, Anhui Provincial Key Lab of Functional Materials & Devices, Hefei University of Technology, Hefei 230009, People's Republic of China.
Guodong LiuDepartment of Chemistry and Biochemistry, North Dakota State University, Fargo, ND 58108, USA.
Chifang PengSchool Food Science & Technology, Jiangnan University, Wuxi 214122, People's Republic of China.
Wei ChenSchool of Biotechnology and Food Engineering, Anhui Provincial Key Lab of Functional Materials & Devices, Hefei University of Technology, Hefei 230009, People's Republic of China.

Funding

Pilot Projects: Core DP30GM103332 · NIGMS · NORTH DAKOTA STATE UNIVERSITY · PI SIBI, MUKUND P. · 2012 to 2016
$4.9M
Development of a Hand-Held Cancer Biomarker MonitorR21CA137703 · NCI · NORTH DAKOTA STATE UNIVERSITY · PI LIU, GUODONG · 2010 to 2011
$338k
NCI NIH HHS R21 CA137703NIGMS NIH HHS P30 GM103332
6 · The paper itself

Abstract

The method referred to as "systemic evolution of ligands by exponential enrichment" (SELEX) was introduced in 1990 and ever since has become an important tool for the identification and screening of aptamers. Such nucleic acids can recognize and bind to their corresponding targets (analytes) with high selectivity and affinity, and aptamers therefore have become attractive alternatives to traditional antibodies not the least because they are much more stable. Meanwhile, they have found numerous applications in different fields including food quality and safety monitoring. This review first gives an introduction into the selection process and to the evolution of SELEX, then covers applications of aptamers in the surveillance of food safety (with subsections on absorptiometric, electrochemical, fluorescent and other methods), and then gives conclusions and perspectives. The SELEX method excels by its features of in vitro, high throughput and ease of operation. This review contains 86 references.

Indexed as

AptamerBiosensorFood safetyRapid detectionSELEX

Identifiers

PMID25419005
PMCPMC4239545

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.