ArticleNature genetics2014
A shared architecture for promoters and enhancers.
Article in Nature genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Accurate de novo transcription unit annotation from run-on and sequencing data.PLoS computational biology · 2026Article
- Characterizing RNA stability genome-wide through combined analysis of PRO-seq and RNA-seq data.BMC biology · 2021Article
- Characterizing Promoter and Enhancer Sequences by a Deep Learning Method.Frontiers in genetics · 2021Article
- Frequency spectra characterization of noncoding human genomic sequences.Genes & genomics · 2020Article
- MPRAnalyze: statistical framework for massively parallel reporter assays.Genome biology · 2019Article
- Systematic interrogation of human promoters.Genome research · 2019Article
- TELS: A Novel Computational Framework for Identifying Motif Signatures of Transcribed Enhancers.Genomics, proteomics & bioinformatics · 2018Article
- Discriminative identification of transcriptional responses of promoters and enhancers after stimulus.Nucleic acids research · 2017Article
- Progress and challenges in bioinformatics approaches for enhancer identification.Briefings in bioinformatics · 2016Review
- High-throughput functional comparison of promoter and enhancer activities.Genome research · 2016Article
- Review
- Non-Coding RNA: Sequence-Specific Guide for Chromatin Modification and DNA Damage Signaling.Frontiers in genetics · 2015Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A new study detects unstable nascent RNAs and uncovers thousands of transcription initiation sites in promoters and enhancers. Detailed analysis shows that these initiation sites have a similar architecture and that they are differentiated by post-transcriptional regulation rather than transcription initiation.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.