Evidence map›Paper›PMID 25418607›Full record

ArticleJournal of the experimental analysis of behavior2015

Impulsive choice, alcohol consumption, and pre-exposure to delayed rewards: II. Potential mechanisms.

Jeffrey S Stein, C Renee Renda, Jay E Hinnenkamp, Gregory J Madden

Abstract read
In one paragraph

Article in Journal of the experimental analysis of behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
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  8. Reducing impulsive choice: VI. Delay-exposure training reduces aversion to delay-signaling stimuli.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020
    Article
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  11. Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeffrey S SteinUtah State University.
C Renee Renda
Jay E Hinnenkamp
Gregory J Madden

Funding

Experimental Manipulations of Impulsivity: Effects on Gambling and Drug TakingR01DA029608 · NIDA · UTAH STATE UNIVERSITY · PI MADDEN, GREGORY J · 2010 to 2013
$957k
NIDA NIH HHS 1R01DA029605NIDA NIH HHS R01 DA029608
6 · The paper itself

Abstract

In a prior study (Stein et al., 2013), we reported that rats pre-exposed to delayed rewards made fewer impulsive choices, but consumed more alcohol (12% wt/vol), than rats pre-exposed to immediate rewards. To understand the mechanisms that produced these findings, we again pre-exposed rats to either delayed (17.5 s; n=32) or immediate (n=30) rewards. In posttests, delay-exposed rats made significantly fewer impulsive choices at 15- and 30-s delays to a larger, later food reward than the immediacy-exposed comparison group. Behavior in an open-field test provided little evidence of differential stress exposure between groups. Further, consumption of either 12% alcohol or isocaloric sucrose in subsequent tests did not differ between groups. Because Stein et al. introduced alcohol concentration gradually (3-12%), we speculate that their group differences in 12% alcohol consumption were not determined by alcohol's pharmacological effects, but by another variable (e.g., taste) that was preserved as an artifact from lower concentrations. We conclude that pre-exposure to delayed rewards generalizes beyond the pre-exposure delay; however, this same experimental variable does not robustly influence alcohol consumption.

Indexed as

Delay DiscountingImpulsive BehaviorAlcohol DrinkingAnimalsConditioning, OperantMaleRatsRats, Long-EvansReaction TimeRewardalcohol self-administrationdelay discountingimpulsive choicelever press, ratopen fieldsucrose self-administration

Identifiers

PMID25418607
PMCPMC4314314

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.