ArticleMicrobiologyOpen2015
Regulation of nitrite resistance of the cytochrome cbb3 oxidase by cytochrome c ScyA in Shewanella oneidensis.
Article in MicrobiologyOpen, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- L-cysteine inhibited the growth ofApplied and environmental microbiology · 2026Article
- Regulation of iron homeostasis by Fur and atypical response regulator SsoR via derepressor-inhibitor oscillation inApplied and environmental microbiology · 2025Article
- Bacterial TANGO2 homologs are heme-trafficking proteins that facilitate biosynthesis of cytochromesmBio · 2023Article
- NapB Restores cytochrome c biosynthesis in bacterial dsbD-deficient mutants.Communications biology · 2022Article
- Complex Interplay of Heme-Copper Oxidases with Nitrite and Nitric Oxide.International journal of molecular sciences · 2022Review
- Promoting Extracellular Electron Transfer ofFrontiers in microbiology · 2021Article
- Plasticity of the peroxidase AhpC links multiple substrates to diverse disulfide-reducing pathways inThe Journal of biological chemistry · 2020Article
- Complex Oxidation of ApocytochromesApplied and environmental microbiology · 2019Article
- Transcriptional regulator ArcA mediates expression of oligopeptide transport systems both directly and indirectly in Shewanella oneidensis.Scientific reports · 2019Article
- CytochromesApplied and environmental microbiology · 2018Article
- Distinct Nitrite and Nitric Oxide Physiologies in Escherichia coli and Shewanella oneidensis.Applied and environmental microbiology · 2018Article
- Loss of OxyR reduces efficacy of oxygen respiration in Shewanella oneidensis.Scientific reports · 2017Article
- NapB in excess inhibits growth of Shewanella oneidensis by dissipating electrons of the quinol pool.Scientific reports · 2016Article
- Shewanella oneidensis FabB: A β-ketoacyl-ACP Synthase That Works with C16:1-ACP.Frontiers in microbiology · 2016Article
- Molecular Underpinnings of Nitrite Effect on CymA-Dependent Respiration in Shewanella oneidensis.Frontiers in microbiology · 2016Article
- K-shell Analysis Reveals Distinct Functional Parts in an Electron Transfer Network and Its Implications for Extracellular Electron Transfer.Frontiers in microbiology · 2016Article
- A Matter of Timing: Contrasting Effects of Hydrogen Sulfide on Oxidative Stress Response in Shewanella oneidensis.Journal of bacteriology · 2015Article
- Positive regulation of the Shewanella oneidensis OmpS38, a major porin facilitating anaerobic respiration, by Crp and Fur.Scientific reports · 2015Article
- Impaired cell envelope resulting from arcA mutation largely accounts for enhanced sensitivity to hydrogen peroxide in Shewanella oneidensis.Scientific reports · 2015Article
- Endogenous generation of hydrogen sulfide and its regulation in Shewanella oneidensis.Frontiers in microbiology · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cytochrome c proteins, as enzymes to exchange electrons with substrates or as pure electron carriers to shuttle electrons, play vital roles in bacterial respiration and photosynthesis. In Shewanella oneidensis, a research model for the respiratory diversity, at least 42 c-type cytochromes are predicted to be encoded in the genome and are regarded to be the foundation of its highly branched electron transport pathways. However, only a small number of c-type cytochromes have been extensively studied. In this study, we identify soluble cytochrome c ScyA as an important factor influencing the nitrite resistance of a strain devoid of the bd oxidase by utilizing a newly developed transposon mutagenesis vector, which enables overexpression of the gene(s) downstream of the insertion site. We show that when in overabundance ScyA facilitates growth against nitrite inhibition by enhancing nitrite resistance of the cbb3 oxidase. Based on the data presented in this study, we suggest two possible mechanisms underlying the observed effect of ScyA: (1) ScyA increases electron flow to the cbb3 oxidase; (2) ScyA promotes nitrite resistance of the cbb3 oxidase, possibly by direct interaction.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.