Trial reportPigment cell & melanoma research2015
Photobiological implications of melanin photoprotection after UVB-induced tanning of human skin but not UVA-induced tanning.
Trial report in Pigment cell & melanoma research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Identification of Genes Expressed in Hyperpigmented Skin Using Meta-Analysis of Microarray Data Sets.The Journal of investigative dermatology · 2015Pooled it
- Unraveling UVA1-Induced Photomodifications of Eumelanin and Pheomelanin in Human Skin: Insights into Pigment Darkening.International journal of molecular sciences · 2026Article
- Regenerative Potential Nanomedicine of Adipocyte Stem Cell-Derived Exosomes in Senescent Skin Tissue.International journal of nanomedicine · 2024Article
- Skin-Aging Pigmentation: Who Is the Real Enemy?Cells · 2022Review
- The Damaging Effects of Long UVA (UVA1) Rays: A Major Challenge to Preserve Skin Health and Integrity.International journal of molecular sciences · 2022Review
- An Integrated Pan-Cancer Analysis and Structure-Based Virtual Screening of GPR15.International journal of molecular sciences · 2019Article
- Estimation of exposure durations for vitamin D production and sunburn risk in Switzerland.Journal of exposure science & environmental epidemiology · 2019Article
- Degraded melanocores are incompetent to protect epidermal keratinocytes against UV damage.Cell cycle (Georgetown, Tex.) · 2018Article
- Induction of retinal-dependent calcium influx in human melanocytes by UVA or UVB radiation contributes to the stimulation of melanosome transfer.Cell proliferation · 2017Article
- The colours of humanity: the evolution of pigmentation in the human lineage.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Derivation of marker gene signatures from human skin and their use in the interpretation of the transcriptional changes associated with dermatological disorders.The Journal of pathology · 2017Article
- Ultraviolet Radiation Exposure and Its Impact on Skin Cancer Risk.Seminars in oncology nursing · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Repetitive suberythemal UVA and/or UVB exposures were used to generate comparable UV-induced tans in human skin over the course of 2 weeks. To evaluate the potential photoprotective values of those UVA- and/or UVB- induced tans and to avoid the confounding issue of residual UV-induced DNA damage, we waited 1 week before challenging those areas with a 1.5 MED of UVA+UVB after which we measure DNA damage. The results show that the type of UV used to induce skin pigmentation affects the redistribution of melanin in the skin and/or de novo melanin synthesis. The UVA-induced tans failed to even provide a minimal SPF of 1.5, which suggests that producing a tan with UVA-rich sunlamps prior to a holiday or vacation is completely counterproductive.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.