Evidence map›Paper›PMID 25417788›Full record

ArticleAIDS research and human retroviruses2015

Short communication: Emergence of novel A/G recombinant HIV-1 strains in Argentina.

María F Fernández, Marcelo D Golemba, Carmen Terrones, Patricia Paradiso, Juan C Nassif, Rosa Bologna, Andrea Mangano, Luisa Sen, Paula C Aulicino

Open access · greenAbstract read
In one paragraph

Article in AIDS research and human retroviruses, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

María F Fernández1 Laboratorio de Biología Celular y Retrovirus, Hospital de Pediatría "Juan P. Garrahan"-CONICET , Buenos Aires, Argentina .
Marcelo D Golemba
Carmen Terrones
Patricia Paradiso
Juan C Nassif
Rosa Bologna
Andrea Mangano
Luisa Sen
Paula C Aulicino
Garrahan Hospital · AREl Hospital General de Agudos Carlos G. Durand · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The predominant circulating HIV-1 strains in South America are subtype B and B/F recombinants with different distributions among countries. However, the emergence of other subtypes is a matter of concern and needs continuous monitoring. We identified three different A/G recombinants in Argentina, two of them in vertically infected children from unlinked mothers and one in an adult female. HIV-1 pol sequences from the children showed novel A/G recombination patterns and no phylogenetic relationship with previously reported South American A/G sequences. The third A/G recombinant was a CRF06_cpx with African origin. The detection of new or unusual subtypes is important to avoid false-negative PCR HIV-1 early diagnosis due to detection failures and for future vaccine development.

Indexed as

Genetic VariationRecombination, GeneticAdultArgentinaChildChild, PreschoolCluster AnalysisFemaleHIV-1HIV InfectionsHumansInfantInfant, NewbornMolecular Sequence DataPhylogenypol Gene Products, Human Immunodeficiency Viruspol Gene Products, Human Immunodeficiency Virus

Identifiers

PMID25417788
PMCPMC4348371
OpenAlexW2322567224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.