Evidence map›Paper›PMID 25417211›Full record

ReviewCellular and molecular life sciences : CMLS2015

Microscale imaging of cilia-driven fluid flow.

Brendan K Huang, Michael A Choma

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Form and function in biological filaments: a physicist's review.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Review
  2. Optical Imaging of Cilia in the Head and Neck.Journal of clinical medicine · 2025
    Review
  3. Review
  4. Review
  5. Optica · 2023
    Article
  6. Light-sheet laser speckle imaging for cilia motility assessment.Computational and structural biotechnology journal · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Microfluidic pumping using artificial magnetic cilia.Microsystems & nanoengineering · 2018
    Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Brendan K HuangDepartment of Biomedical Engineering, Yale University, New Haven, USA, brendan.huang@yale.edu.
Michael A Choma
Yale University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
Quantitative optical imaging of cilia-driven fluid flowR01HL118419 · NHLBI · YALE UNIVERSITY · PI KHOKHA, MUSTAFA K · 2013 to 2017
$2.0M
NHLBI NIH HHS 1R01HL118419-01NHLBI NIH HHS R01 HL118419NIGMS NIH HHS T32 GM007205NIGMS NIH HHS T32GM07205
6 · The paper itself

Abstract

Cilia-driven fluid flow is important for multiple processes in the body, including respiratory mucus clearance, gamete transport in the oviduct, right-left patterning in the embryonic node, and cerebrospinal fluid circulation. Multiple imaging techniques have been applied toward quantifying ciliary flow. Here, we review common velocimetry methods of quantifying fluid flow. We then discuss four important optical modalities, including light microscopy, epifluorescence, confocal microscopy, and optical coherence tomography, that have been used to investigate cilia-driven flow.

Indexed as

AnimalsCiliaColoring AgentsEquipment DesignHumansMicrofluidic Analytical TechniquesMicroscopyOptical ImagingRheologySpectrometry, FluorescenceColoring Agents

Identifiers

PMID25417211
PMCPMC4605231
OpenAlexW2036956044

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.