Trial reportEuropean journal of applied physiology2015
Effect of low-level laser therapy on muscle adaptation to knee extensor eccentric training.
Trial report in European journal of applied physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06380179 (Assessing the Impact of Post-Exercise Photobiomodulation Application on Performance, Recovery, and Behavioral State in Trained Special Operator Population), which is not on this map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessing the Impact of Post-Exercise Photobiomodulation Application on Performance, Recovery, and Behavioral State in Trained Special Operator Population
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Effects of photobiomodulation therapy on the functional performance of healthy individuals: a systematic review with meta-analysis.Lasers in medical science · 2023Pooled it
- Photobiomodulation therapy for the improvement of muscular performance and reduction of muscular fatigue associated with exercise in healthy people: a systematic review and meta-analysis.Lasers in medical science · 2018Pooled it
- Effects of resistance training with/without Photobiomodulation on muscle and respiratory function in difficult-to-control asthma: a randomized trial.Lasers in medical science · 2026Trial
- Immediate effects of photobiomodulation on maximum tongue pressure: a randomized clinical study.CoDAS · 2025Trial
- Photobiomodulation therapy (red/NIR LEDs) reduced the length of stay in intensive care unit and improved muscle function: A randomized, triple-blind, and sham-controlled trial.Journal of biophotonics · 2024Trial
- Quadriceps femoris performance after resistance training with and without photobiomodulation in elderly women: a randomized clinical trial.Lasers in medical science · 2019Trial
- Acute effect of photobiomodulation therapy on handgrip strength of chronic kidney disease patients during hemodialysis.Lasers in medical science · 2019Trial
- Effects of photobiomodulation therapy associated with resistance training in elderly men: a randomized double-blinded placebo-controlled trial.European journal of applied physiology · 2019Trial
- Effect of laser treatment on postural control parameters in patients with chronic nonspecific low back pain: a randomized placebo-controlled trial.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019Trial
- Low-level laser therapy improves the VOLasers in medical science · 2018Trial
- Effects of low-level laser therapy applied before or after plyometric exercise on muscle damage markers: randomized, double-blind, placebo-controlled trial.Lasers in medical science · 2016Trial
- Low-level laser therapy reduces the fatigue index in the ankle plantar flexors of healthy subjects.Lasers in medical science · 2016Trial
- What is the best moment to apply phototherapy when associated to a strength training program? A randomized, double-blinded, placebo-controlled trial : Phototherapy in association to strength training.Lasers in medical science · 2016Trial
- Trial
- Isokinetic eccentric training is more effective than constant load eccentric training for quadriceps rehabilitation following anterior cruciate ligament reconstruction: a randomized controlled trial.Brazilian journal of physical therapyTrial
- Photobiomodulation Combined with Moderate or High-Intensity Interval Training on Oxygen Consumption and Exercise Tolerance in Patients with Heart Failure.Arquivos brasileiros de cardiologia · 2025Article
- Effects of photobiomodulation therapy combined with static magnetic field on training adaptations and detraining responses: a randomised placebo-controlled trial.BMJ open sport & exercise medicine · 2025Article
- Photobiomodulation as Medicine: Low-Level Laser Therapy (LLLT) for Acute Tissue Injury or Sport Performance Recovery.Journal of functional morphology and kinesiology · 2024Review
- Therapeutic Photobiomodulation Before Strenuous Exercise Attenuates Shoulder Muscle Fatigue.Journal of athletic training · 2024Article
- Effects of photobiomodulation therapy associated with motor control exercise for chronic non-specific low back pain: protocol for a randomised placebo-controlled trial.BMJ open sport & exercise medicine · 2024Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeEccentric training has been popularized for physical conditioning and prevention/rehabilitation of musculoskeletal disorders, especially due to the expressive responses in terms of muscular strength gain. In view of evidence that low-level laser therapy (LLLT) is able to increase exercise performance and accelerate post-exercise recovery, the aim of this study was to verify the effect of LLLT on hypertrophy and strengthening of knee extensor muscles submitted to eccentric training.
methodThirty healthy male subjects were randomized into three groups: Control Group (CG), Training Group (TG) and Training + LLLT Group (TLG). CG received no intervention, while TG and TLG were engaged on an 8-week knee extensor isokinetic eccentric training program. Only subjects from TLG were treated with LLLT (wavelength = 810 nm; power output = 200 mW; total dosage = 240 J) before each training session. Knee extensor muscle thickness and peak torque were assessed through ultrasonography and isokinetic dynamometry, respectively.
resultsCG presented no changes in any variable throughout the study, while eccentric training led to significant increases in muscle thickness and peak torque in TG and TLG. Subjects from TLG reached significantly higher percent changes compared to subjects from TG for sum of muscles' thicknesses (15.4 vs. 9.4%), isometric peak torque (20.5 vs. 13.7%), and eccentric peak torque (32.2 vs. 20.0%).
conclusionLLLT applied before eccentric training sessions seems to improve the hypertrophic response and muscular strength gain in healthy subjects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.