ArticleCancer microenvironment : official journal of the International Cancer Microenvironment Society2014
Orthotopic mouse models of tumor metastasis expressing fluorescent reporters produce imageable circulating tumor cells.
Article in Cancer microenvironment : official journal of the International Cancer Microenvironment Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- The Role of RASSF1C in the Tumor Microenvironment.Current issues in molecular biology · 2023Article
- Clinical significance of circulating tumor cells from lung cancer patients using microfluidic chip.Clinical and experimental medicine · 2018Article
- Detecting Tumor Metastases: The Road to Therapy Starts Here.Advances in cancer research · 2016Review
- About seed and soil.Cancer microenvironment : official journal of the International Cancer Microenvironment Society · 2014Article
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Authors and funding
1 author.
Funding
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Abstract
Circulating tumor cells (CTC) are of high importance, since they are potential metastatic precursors and are readily available for prognostic analysis and treatment testing. In this review, we demonstrate the great power that green fluorescent protein (GFP) labeling and orthotopic mouse models of cancer confer to the study of CTCs for isolation and characterization, including metastatic testing in mice and the chick embryo as well as drug response testing in vitro. We also describe a facile method to label patient CTCs ex vivo using a telomerase-expressing GFP-containing adenovirus that will allow the CTC studies described in this review to be translated clinically.
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Registered trials
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