Evidence map›Paper›PMID 25417100›Full record

ArticleCell2014

A deeper look into translation initiation.

Andrei A Korostelev

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Poly(G)RNA biology · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Andrei A KorostelevRNA Therapeutics Institute, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA 01605, USA. Electronic address: andrei.korostelev@umassmed.edu.

Funding

Structural bases for cellular stress responses mediated by stalled translationR01GM106105 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KOROSTELEV, ANDREI · 2013 to 2017
$1.6M
Medical Research Council MC_U105184332NIGMS NIH HHS R01 GM106105
6 · The paper itself

Abstract

Eukaryotic translation initiation requires coordinated assembly of a remarkable array of initiation factors onto the small ribosomal subunit to select an appropriate mRNA start codon. Studies from Erzberger et al. and Hussain et al. bring new insights into this mechanism by looking at early and late initiation intermediates.

Indexed as

Peptide Chain Initiation, TranslationalAnimalsEukaryotic Initiation Factor-1Eukaryotic Initiation Factor-3Eukaryotic Initiation FactorsHumansKluyveromycesRibosome Subunits, Small, EukaryoticSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsEukaryotic Initiation Factor-1Eukaryotic Initiation Factor-3Eukaryotic Initiation FactorsSaccharomyces cerevisiae Proteins

Identifiers

PMID25417100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.