Evidence map›Paper›PMID 25416835›Full record

ArticleJournal of biomechanical engineering2015

Measurement systems for cell adhesive forces.

Dennis W Zhou, Andrés J García

Open access · greenAbstract read
In one paragraph

Article in Journal of biomechanical engineering, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Impact of adhesive area on cellular traction force and spread area.Journal of biomedical materials research. Part A · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Hydrodynamic shear-based purification of cancer cells with enhanced tumorigenic potential.Integrative biology : quantitative biosciences from nano to macro · 2020
    Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dennis W Zhou
Andrés J García
Georgia Institute of Technology · US

Funding

Focal Adhesions in Cell Adhesion StrengtheningR01GM065918 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI GARCIA, ANDRES J · 2002 to 2011
$2.6M
NIGMS NIH HHS R01 GM065918
6 · The paper itself

Abstract

Cell adhesion to the extracellular matrix (ECM) involves integrin receptor-ligand binding and clustering to form focal adhesion (FA) complexes, which mechanically link the cell's cytoskeleton to the ECM and regulate fundamental cell signaling pathways. Although elucidation of the biochemical events in cell-matrix adhesive interactions is rapidly advancing, recent studies show that the forces underlying cell-matrix adhesive interactions are also critical to cell responses. Therefore, multiple measurement systems have been developed to quantify the spatial and temporal dynamics of cell adhesive forces, and these systems have identified how mechanical events influence cell phenotype and FA structure-function relationships under physiological and pathological settings. This review focuses on the development, methodology, and applications of measurement systems for probing (a) cell adhesion strength and (b) 2D and 3D cell traction forces.

Indexed as

Mechanical PhenomenaBiomechanical PhenomenaCell AdhesionExtracellular MatrixHumansInduced Pluripotent Stem CellsPhenotypeShear StrengthStress, Mechanical

Identifiers

PMID25416835
PMCPMC4347357
OpenAlexW1993057045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.