ArticleBMC surgery2014
Impact of comorbidities on postoperative complications in patients undergoing laparoscopy-assisted gastrectomy for gastric cancer.
Article in BMC surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 31 citations in OpenAlex.
- Association between the Parkland grading scale score and postoperative complications according to the Clavien-Dindo classification in emergency laparoscopic cholecystectomy.Updates in surgery · 2026Article
- Laparoscopic gastrectomy reduced peritoneal recurrence in Borrmann type IV gastric cancer: a retrospective cohort study with propensity score matching.Surgical endoscopy · 2025Article
- Assessment of postoperative complications and their risk factors in general surgery using clavien-dindo classification.Bioinformation · 2025Article
- Comorbidities Associated With Increased Likelihood of Postoperative Surgical Site Infection in Patients Treated for Hand or Finger Fracture and/or Dislocations.Hand (New York, N.Y.) · 2024Article
- Complication After Gastrectomy for Gastric Cancer According to Hospital Volume: Based on Korean Gastric Cancer Association-Led Nationwide Survey Data.Journal of gastric cancer · 2023Article
- Article
- The impact of the prognostic nutritional index (PNI) in gastric cancer.Langenbeck's archives of surgery · 2022Article
- The role of postoperative neutrophil-to-lymphocyte ratio as a predictor of postoperative major complications following total gastrectomy for gastric cancer.Annals of surgical treatment and research · 2022Article
- Article
- Preoperative predictors of postoperative complications after gastric cancer resection.Surgery today · 2020Review
- Intraoperative Body Fluid Amylase as a Novel Indicator of Postgastrectomy Pancreatic Fistula.World journal of surgery · 2019Article
- Article
- Impact of the Age-adjusted Charlson comorbidity index on the short- and long-term outcomes of patients undergoing curative gastrectomy for gastric cancer.Journal of Cancer · 2019Article
- Impact of Various Types of Comorbidities on the Outcomes of Laparoscopic Total Gastrectomy in Patients with Gastric Carcinoma.Journal of gastric cancer · 2018Article
- Effect of comorbidities on postoperative complications in patients with gastric cancer after laparoscopy-assisted total gastrectomy: results from an 8-year experience at a large-scale single center.Surgical endoscopy · 2017Article
- Clinical and surgical factors associated with organ/space surgical site infection after laparoscopic gastrectomy for gastric cancer.Surgical endoscopy · 2017Article
- C-reactive protein can be an early predictor of postoperative complications after gastrectomy for gastric cancer.Surgical endoscopy · 2017Article
- Article
- Observational
- Clinical significance of lymphadenectomy in patients with gastric cancer.World journal of gastrointestinal oncology · 2016Review
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5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundComorbidity is a predictor of postoperative complications (PCs) in gastrectomy. However, it remains unclear which comorbidities are predictors of PCs in patients who undergo laparoscopy-assisted gastrectomy (LAG). Clinically, insufficient lymphadenectomy (LND) is sometimes performed in high-risk patients, although the impact on PCs and outcomes remains unclear.
methodsWe retrospectively studied 529 patients with gastric cancer (GC) who underwent LAG. PCs were defined as grade 2 or higher events according to the Clavien-Dindo classification. We evaluated various comorbidities as risk factors for PCs and examined the impact of insufficient LND on PCs in patients with risky comorbidities.
resultA total of 87 (16.4%) patients had PCs. There was no PC-related death. On univariate analysis, heart disease, central nervous system (CNS) disease, liver disease, renal dysfunction, and restrictive pulmonary dysfunction were significantly associated with PCs. Both liver disease and heart disease were significant independent risk factors for PCs on multivariate analysis (odds ratio [OR] = 3.25, p = 0.022; OR = 2.36, p = 0.017, respectively). In patients with one or more risky comorbidity, insufficient LND did not significantly decrease PCs (p = 0.42) or shorten GC-specific survival (p = 0.25).
conclusionIn patients who undergo LAG for GC, the presence of heart disease or liver disease is an independent risk factor for PC. Insufficient LND (for example, D1+ for advanced GC) might be permissible in high-risk patients, because although it did not reduce PCs, it had no negative impact on GC-specific survival.
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