Evidence map›Paper›PMID 25416409›Full record

ReviewCancer prevention research (Philadelphia, Pa.)2015

Physical inactivity and low fitness deserve more attention to alter cancer risk and prognosis.

Fabian Sanchis-Gomar, Alejandro Lucia, Thomas Yvert, Ana Ruiz-Casado, Helios Pareja-Galeano, Alejandro Santos-Lozano, Carmen Fiuza-Luces, Nuria Garatachea, Giuseppe Lippi, Claude Bouchard and 1 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Cancer prevention research (Philadelphia, Pa.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
11.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. A Cross-Sectional Study on Self-Perceived Health and Physical Activity Level in the Spanish Population.International journal of environmental research and public health · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. "Stay-at-Home" Lifestyle Effect on Weight Gain during the COVID-19 Outbreak Confinement in China.International journal of environmental research and public health · 2021
    Article
  19. Article
  20. Dietary practices of adult Egyptians before and during the COVID-19 lockdown.Nutrire : revista de Sociedade Brasileira de Alimentacao e Nutricao = journal of the Brazilian Society of Food and Nutrition · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 3 countries.

Fabian Sanchis-GomarFaculty of Medicine, Department of Physiology, University of Valencia, Valencia, Spain. Fundación Investigación Hospital Clínico Universitario/INCLIVA. Spain.
Alejandro LuciaResearch Institute of Hospital 12 de Octubre ("i+12"), Madrid, Spain. European University, Madrid, Spain.
Thomas YvertSchool of Doctorate Studies and Research, Universidad Europea de Madrid, Madrid, Spain.
Ana Ruiz-CasadoDepartment of Oncology, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain.
Helios Pareja-GaleanoFaculty of Medicine, Department of Physiology, University of Valencia, Valencia, Spain. Fundación Investigación Hospital Clínico Universitario/INCLIVA. Spain.
Alejandro Santos-LozanoResearch Institute of Hospital 12 de Octubre ("i+12"), Madrid, Spain. Department of Biomedical Sciences, University of León, León, Spain.
Carmen Fiuza-LucesResearch Institute of Hospital 12 de Octubre ("i+12"), Madrid, Spain. European University, Madrid, Spain.
Nuria GaratacheaResearch Institute of Hospital 12 de Octubre ("i+12"), Madrid, Spain. Faculty of Health and Sport Sciences, University of Zaragoza, Huesca, Spain.
Giuseppe LippiLaboratory of Clinical Chemistry and Hematology, Academic Hospital of Parma, Parma, Italy.
Claude BouchardHuman Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana.
Nathan A BergerCenter for Science, Health and Society, Case Comprehensive Cancer Center, Case Western Reserve University, School of Medicine, Cleveland, Ohio. nab@case.edu.
Research Institute Hospital 12 de Octubre · ESUniversitat de València · ESCase Western Reserve University · USHospital Universitario Puerta de Hierro Majadahonda · ESPennington Biomedical Research Center · USUniversidad de Zaragoza · ESUniversidad Europea · ESUniversity of Parma · IT

Funding

Targeting 15-PGDH in Colon Cancer Prognosis, Prediction, Treatment and PreventionP50CA150964 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI MARKOWITZ, SANFORD D. · 2011 to 2022
$24.6M
Whole Exome Approaches for Esophageal Adenocarcinoma Susceptibility GenesU54CA163060 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI CHAK, AMITABH, GUDA, KISHORE · 2011 to 2022
$14.0M
HERITAGE STUDY: GENETICS, EXERCISE &RISK FACTORSR01HL045670 · NHLBI · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI RANKINEN, TUOMO · 1992 to 2010
$6.8M
NCI NIH HHS P50 CA150964NCI NIH HHS U54 CA163060NHLBI NIH HHS HL-045670NHLBI NIH HHS R01 HL045670
6 · The paper itself

Abstract

Sedentary lifestyle is associated with elevated cancer risk whereas regular physical activity (PA) and high cardiorespiratory fitness (CRF) have the opposite effect, with several biologic mechanisms mediating such associations. There is a need for lifestyle interventions aimed at increasing the PA levels and CRF of the general population and particularly cancer survivors. Furthermore, provocative data suggest a dose-dependent benefit of increasing levels of PA and/or CRF against cancer risk or mortality. Thus, current PA guidelines (≥150 min/wk of moderate-to-vigorous PA) may not be sufficiently rigorous for preventing cancer nor for extending cancer survivorship. Research targeting this issue is urgently needed. Promoting regular PA along with monitoring indicators of CRF and adiposity may provide powerful strategies to prevent cancer in populations, help patients with cancer more effectively deal with their disease and enhance secondary prevention programs in those who are affected by cancer.

Indexed as

Sedentary BehaviorExerciseHumansNeoplasmsPhysical FitnessPrognosisRisk Factors

Identifiers

PMID25416409
PMCPMC4315717
OpenAlexW2330544401

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.