Evidence map›Paper›PMID 25416075›Full record

ArticleAIDS and behavior2015

"I Have Remained Strong Because of That Food": Acceptability and Use of Lipid-Based Nutrient Supplements Among Pregnant HIV-Infected Ugandan Women Receiving Combination Antiretroviral Therapy.

Sera Young, Barnabas Natamba, Flavia Luwedde, Dorcas Nyafwono, Ben Okia, Beth Osterbauer, Paul Natureeba, Lynn Johnson, Chloe Michel, Amy Zheng and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in AIDS and behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00993031 (Protease Inhibitors to Reduce Malaria Morbidity in HIV-Infected Pregnant Women), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00993031 phase3completednot on this map

Protease Inhibitors to Reduce Malaria Morbidity in HIV-Infected Pregnant Women

TypeinterventionalSponsorUniversity of California, San FranciscoRan2009 to 2013Enrolled389ConditionsMalaria, HIV InfectionsArmsLopinavir/ritonavir, Efavirenz, Zidovudine, Lamivudine
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Sera YoungDivision of Nutritional Sciences, Cornell University, 113 Savage Hall, Ithaca, NY, 14850, USA, sera.young@cornell.edu.
Barnabas Natamba
Flavia Luwedde
Dorcas Nyafwono
Ben Okia
Beth Osterbauer
Paul Natureeba
Lynn Johnson
Chloe Michel
Amy Zheng
Marion Robine
Jane Achan
Edwin Charlebois
Deb Cohan
Diane Havlir
Cornell University · USUniversity of California, San Francisco · USMUJHU Research Collaboration · UGMakerere University · UGSan Francisco AIDS Foundation · US

Funding

San Francisco Vaccine and Prevention UnitUM1AI069496 · NIAID · PUBLIC HEALTH FOUNDATION ENTERPRISES · PI Susan Buchbinder, Diane V Havlir · 2012 to 2026
$30.5M
The immunologic consequences of prenatal exposure to malariaP01HD059454 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAVLIR, DIANE V · 2008 to 2017
$22.6M
Health Consequences of Food & Nutrition Insecurity for HIV+ Women & Their InfantsK01MH098902 · NIMH · NORTHWESTERN UNIVERSITY · PI YOUNG, SERA LEWISE · 2012 to 2016
$854k
NIAID NIH HHS UM1 AI069496NICHD NIH HHS HD059454NICHD NIH HHS HD059454-03S1NICHD NIH HHS P01 HD059454NIMH NIH HHS K01 MH098902PEPFAR
6 · The paper itself

Abstract

We evaluated the acceptability and use of macronutrient supplementation among HIV-infected pregnant Ugandan women receiving antiretroviral therapy in a clinical study (NCT 00993031). We first conducted formative research among 56 pregnant and lactating women to select a supplement regimen. Acceptability and use of the supplementation regimen (35 sachets of lipid-based nutrient supplements (LNS) and 4 or 6 kg of instant soy porridge for the household provided monthly) were evaluated among 87 pregnant women. Organoleptic assessments of LNS were favorable. Participants reported consuming LNS a mean of 6.1 days per week, and adherence to recommended consumption behaviors (e.g. frequency, quantity, not sharing) was >80 %. Few women reported negative social consequences of supplementation. The majority of participants also consumed most of the porridge intended for the household. In sum, LNS was acceptable and used regularly. Larger studies to evaluate physical and psychosocial consequences of LNS during pregnancy among HIV-infected women are warranted.

Indexed as

Consumer BehaviorDietary SupplementsFood, FortifiedAdultAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveBreast FeedingDietary FatsFemaleFollow-Up StudiesHIV InfectionsHumansInterviews as TopicMalnutritionPatient Acceptance of Health CarePregnancyAnti-Retroviral AgentsDietary Fats

Identifiers

PMID25416075
PMCPMC4441598
OpenAlexW2087051679

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.