ArticleIEEE transactions on medical imaging2015
Global linking of cell tracks using the Viterbi algorithm.
Article in IEEE transactions on medical imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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Who cites it
57 citing papers in PubMed.
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- An automated cell-tracking pipeline for the analysis of neutrophil dynamics.Frontiers in bioinformatics · 2026Article
- Contrastive learning for cell division detection and tracking in live cell imaging data.BMC bioinformatics · 2025Article
- Pushing the limits of automated cell tracking.Nature methods · 2025Article
- Cell tracking with accurate error prediction.Nature methods · 2025Article
- Oncostatin M orchestrates collective epithelial migration via HIF1A activation.bioRxiv : the preprint server for biology · 2025Article
- Microenvironmental signals combine to induce non-additive molecular and phenotypic responses in mammary epithelial cells.iScience · 2025Article
- Pooled optical screening in bacteria using chromosomally expressed barcodes.Communications biology · 2025Article
- Cell-TRACTR: A transformer-based model for end-to-end segmentation and tracking of cells.PLoS computational biology · 2025Article
- Scale selection and machine learning based cell segmentation and tracking in time lapse microscopy.Scientific reports · 2025Article
- Cellular behavior analysis from live-cell imaging of TCR T cell-cancer cell interactions.bioRxiv : the preprint server for biology · 2024Article
- Three-dimensional localization and tracking of chromosomal loci throughout the Escherichia coli cell cycle.Communications biology · 2024Article
- CMTT-JTracker: a fully test-time adaptive framework serving automated cell lineage construction.Briefings in bioinformatics · 2024Article
- The Escherichia coli chromosome moves to the replisome.Nature communications · 2024Article
- Versatile multiple object tracking in sparse 2D/3D videos via deformable image registration.PLoS computational biology · 2024Article
- Ensemble Deep Learning Object Detection Fusion for Cell Tracking, Mitosis, and Lineage.IEEE open journal of engineering in medicine and biology · 2024Article
- Article
- Deep learning classification for macrophage subtypes through cell migratory pattern analysis.Frontiers in cell and developmental biology · 2024Article
- CellTool: An Open-Source Software Combining Bio-Image Analysis and Mathematical Modeling for the Study of DNA Repair Dynamics.International journal of molecular sciences · 2023Article
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Authors and funding
4 authors.
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Abstract
Automated tracking of living cells in microscopy image sequences is an important and challenging problem. With this application in mind, we propose a global track linking algorithm, which links cell outlines generated by a segmentation algorithm into tracks. The algorithm adds tracks to the image sequence one at a time, in a way which uses information from the complete image sequence in every linking decision. This is achieved by finding the tracks which give the largest possible increases to a probabilistically motivated scoring function, using the Viterbi algorithm. We also present a novel way to alter previously created tracks when new tracks are created, thus mitigating the effects of error propagation. The algorithm can handle mitosis, apoptosis, and migration in and out of the imaged area, and can also deal with false positives, missed detections, and clusters of jointly segmented cells. The algorithm performance is demonstrated on two challenging datasets acquired using bright-field microscopy, but in principle, the algorithm can be used with any cell type and any imaging technique, presuming there is a suitable segmentation algorithm.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.