ArticleAJR. American journal of roentgenology2014
Diagnostic performance of dual-energy CT stress myocardial perfusion imaging: direct comparison with cardiovascular MRI.
Article in AJR. American journal of roentgenology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 36 citations in OpenAlex.
- Predicting Chronic Myocardial Ischemia Using CCTA-Based Radiomics Machine Learning Nomogram.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Trial
- Exploring the diagnostic effectiveness for myocardial ischaemia based on CCTA myocardial texture features.BMC cardiovascular disorders · 2021Article
- Diagnostic value of quantitative parameters for myocardial perfusion assessment in patients with suspected coronary artery disease by single- and dual-energy computed tomography myocardial perfusion imaging.International journal of cardiology. Heart & vasculature · 2021Article
- Cardiac CT perfusion and FFRCardiovascular diagnosis and therapy · 2020Review
- Dual-energy CT and coronary imaging.Cardiovascular diagnosis and therapy · 2020Review
- Role of Cardiac Computed Tomography in the Diagnosis of Left Ventricular Myocardial Diseases.Journal of cardiovascular imaging · 2019Review
- Assessment of Left Ventricular Myocardial Diseases with Cardiac Computed Tomography.Korean journal of radiology · 2019Review
- CT Myocardial Perfusion Imaging: A New Frontier in Cardiac Imaging.BioMed research international · 2018Review
- Myocardial ischemia testing with computed tomography: emerging strategies.Cardiovascular diagnosis and therapy · 2017Review
- Accuracy of iodine quantification using dual energy CT in latest generation dual source and dual layer CT.European radiology · 2017Article
- Infarct characterization using CT.Cardiovascular diagnosis and therapy · 2017Review
- Myocardial blood flow quantification for evaluation of coronary artery disease by computed tomography.Cardiovascular diagnosis and therapy · 2017Review
- Quantitative myocardial perfusion with stress dual-energy CT: iodine concentration differences between normal and ischemic or necrotic myocardium. Initial experience.European radiology · 2016Article
- Multidetector dual-energy CT evaluation of combined partial anomalous pulmonary venous return and bronchial atresia.BJR case reports · 2016Article
- Can Erectile Dysfunction in Young Patients Serve as a Surrogate Marker for Coronary Artery Disease?Journal of clinical and diagnostic research : JCDR · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveThe purpose of this study was to assess the diagnostic performance of stress perfusion dual-energy CT (DECT) and its incremental value when used with coronary CT angiography (CTA) for identifying hemodynamically significant coronary artery disease. SUBJECTS AND
methodsOne hundred patients with suspected or known coronary artery disease without chronic myocardial infarction detected with coronary CTA underwent stress perfusion DECT, stress cardiovascular perfusion MRI, and invasive coronary angiography (ICA). Stress perfusion DECT and cardiovascular stress perfusion MR images were used for detecting perfusion defects. Coronary CTA and ICA were evaluated in the detection of ≥50% coronary stenosis. The diagnostic performance of coronary CTA for detecting hemo-dynamically significant stenosis was assessed before and after stress perfusion DECT on a per-vessel basis with ICA and cardiovascular stress perfusion MRI as the reference standard.
resultsThe performance of stress perfusion DECT compared with cardiovascular stress perfusion MRI on a per-vessel basis in the detection of perfusion defects was sensitivity, 89%; specificity, 74%; positive predictive value, 73%; negative predictive value, 90%. Per segment, these values were sensitivity, 76%; specificity, 80%; positive predictive value, 63%; and negative predictive value, 88%. Compared with ICA and cardiovascular stress perfusion MRI per vessel territory the sensitivity, specificity, positive predictive value, and negative predictive value of coronary CTA were 95%, 61%, 61%, and 95%. The values for stress perfusion DECT were 92%, 72%, 68%, and 94%. The values for coronary CTA and stress perfusion DECT were 88%, 79%, 73%, and 91%. The ROC AUC increased from 0.78 to 0.84 (p=0.02) with the use of coronary CTA and stress perfusion DECT compared with coronary CTA alone.
conclusionStress perfusion DECT plays a complementary role in enhancing the accuracy of coronary CTA for identifying hemodynamically significant coronary stenosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.