ArticleMarine drugs2014
Inhibition of bacterial quorum sensing by extracts from aquatic fungi: first report from marine endophytes.
Article in Marine drugs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 61 citations in OpenAlex.
- Antifouling Lipids from Marine Fungi of the Beibu Gulf.Metabolites · 2025Article
- Scientific Investigation of Antifouling Activity from Biological Agents and Distribution of Marine Foulers-Coastal Areas of Tamil Nadu.Applied biochemistry and biotechnology · 2024Review
- A roadmap to understanding diversity and function of coral reef-associated fungi.FEMS microbiology reviews · 2022Article
- An update on T2-toxins: metabolism, immunotoxicity mechanism and human assessment exposure of intestinal microbiota.Heliyon · 2022Review
- The Good, the Bad, and the Ugly: Mycotoxin Production During Postharvest Decay and Their Influence on Tritrophic Host-Pathogen-Microbe Interactions.Frontiers in microbiology · 2021Review
- Metabolic profiling of Fusarium oxysporum f. sp. conglutinans race 2 in dual cultures with biocontrol agents Bacillus amyloliquefaciens, Pseudomonas aeruginosa, and Trichoderma harzianum.Folia microbiologica · 2019Article
- Saline Environments as a Source of Potential Quorum Sensing Disruptors to Control Bacterial Infections: A Review.Marine drugs · 2019Review
- Quorum Sensing Inhibitors from Marine Microorganisms and Their Synthetic Derivatives.Marine drugs · 2019Review
- Mycotoxins in Conversation With Bacteria and Fungi.Frontiers in microbiology · 2019Review
- Bacterial-Fungal Interactions in the Kelp Endomicrobiota Drive Autoinducer-2 Quorum Sensing.Frontiers in microbiology · 2019Article
- Quorum sensing intervened bacterial signaling: Pursuit of its cognizance and repression.Journal, genetic engineering & biotechnology · 2018Review
- Review
- Shoot the Message, Not the Messenger-Combating Pathogenic Virulence in Plants by Inhibiting Quorum Sensing Mediated Signaling Molecules.Frontiers in plant science · 2017Review
- Deep Subseafloor Fungi as an Untapped Reservoir of Amphipathic Antimicrobial Compounds.Marine drugs · 2016Article
- Hydrolysis mechanism of methyl parathion evidenced by Q-Exactive mass spectrometry.Environmental science and pollution research international · 2015Article
- Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In our search for quorum-sensing (QS) disrupting molecules, 75 fungal isolates were recovered from reef organisms (endophytes), saline lakes and mangrove rhizosphere. Their QS inhibitory activity was evaluated in Chromobacterium violaceum CVO26. Four strains of endophytic fungi stood out for their potent activity at concentrations from 500 to 50 μg mL-1. The molecular characterization, based on the internal transcribed spacer (ITS) region sequences (ITS1, 5.8S and ITS2) between the rRNA of 18S and 28S, identified these strains as belonging to four genera: Sarocladium (LAEE06), Fusarium (LAEE13), Epicoccum (LAEE14), and Khuskia (LAEE21). Interestingly, three came from coral species and two of them came from the same organism, the coral Diploria strigosa. Metabolic profiles obtained by Liquid Chromatography-High Resolution Mass Spectrometry (LC-HRMS) suggest that a combination of fungal secondary metabolites and fatty acids could be the responsible for the observed activities. The LC-HRMS analysis also revealed the presence of potentially new secondary metabolites. This is, to the best of our knowledge, the first report of QS inhibition by marine endophytic fungi.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.