ReviewMarine drugs2014
Emerging biomedical applications of nano-chitins and nano-chitosans obtained via advanced eco-friendly technologies from marine resources.
Review in Marine drugs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 159 citations in OpenAlex.
- The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction.Medicina oral, patologia oral y cirugia bucal · 2016Trial
- Spectroscopic approaches for structural analysis of extracted chitosan generated from chitin deacetylated for escalated periods.BMC chemistry · 2025Article
- Nanochitin and Nanochitosan in Pharmaceutical Applications: Innovations, Applications, and Future Perspective.Pharmaceutics · 2025Review
- A Mini-Review: Fabrication of Polysaccharide Composite Materials Based on Self-Assembled Chitin Nanofibers.Materials (Basel, Switzerland) · 2024Review
- Hydrogelation from Self-Assembled and Scaled-Down Chitin Nanofibers by the Modification of Highly Polar Substituents.Gels (Basel, Switzerland) · 2023Review
- Nanochitin: Chemistry, Structure, Assembly, and Applications.Chemical reviews · 2022Review
- Chitosan-Based Biomaterial Scaffolds for the Repair of Infected Bone Defects.Frontiers in bioengineering and biotechnology · 2022Review
- Review
- Nanomaterials in Dentistry: State of the Art and Future Challenges.Nanomaterials (Basel, Switzerland) · 2020Review
- Extraction of Nanochitin from Marine Resources and Fabrication of Polymer Nanocomposites: Recent Advances.Polymers · 2020Review
- Effect of Chitosan as a Cross-Linker on Matrix Metalloproteinase Activity and Bond Stability with Different Adhesive Systems.Marine drugs · 2020Article
- Synthesis of Chitosan Beads Incorporating Graphene Oxide/Titanium Dioxide Nanoparticles for In Vivo Studies.Molecules (Basel, Switzerland) · 2020Article
- 3D Chitin Scaffolds of Marine Demosponge Origin for Biomimetic Mollusk Hemolymph-Associated BiomineralizationMarine drugs · 2020Article
- Biocatalytic oligomerization-induced self-assembly of crystalline cellulose oligomers into nanoribbon networks assisted by organic solvents.Beilstein journal of nanotechnology · 2019Article
- Biopolymer nanofibrils: structure, modeling, preparation, and applications.Progress in polymer science · 2018Article
- Retraction: Azuma, K. et al. Chitin, Chitosan, and Its Derivatives for Wound Healing: Old and New Materials. J. Funct. Biomater. 2015, 6, 104⁻142.Journal of functional biomaterials · 2018Article
- Preparation of Self-Assembled Chitin Nanofiber-Natural Rubber Composite Sheets and Porous Materials.Biomolecules · 2017Article
- Nanostructurally Controlled Hydrogel Based on Small-Diameter Native Chitin Nanofibers: Preparation, Structure, and Properties.ChemSusChem · 2016Article
- Strategies to Maximize the Potential of Marine Biomaterials as a Platform for Cell Therapy.Marine drugs · 2016Review
- Genipin-Crosslinked Chitosan Gels and Scaffolds for Tissue Engineering and Regeneration of Cartilage and Bone.Marine drugs · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present review article is intended to direct attention to the technological advances made in the 2010-2014 quinquennium for the isolation and manufacture of nanofibrillar chitin and chitosan. Otherwise called nanocrystals or whiskers, n-chitin and n-chitosan are obtained either by mechanical chitin disassembly and fibrillation optionally assisted by sonication, or by e-spinning of solutions of polysaccharides often accompanied by poly(ethylene oxide) or poly(caprolactone). The biomedical areas where n-chitin may find applications include hemostasis and wound healing, regeneration of tissues such as joints and bones, cell culture, antimicrobial agents, and dermal protection. The biomedical applications of n-chitosan include epithelial tissue regeneration, bone and dental tissue regeneration, as well as protection against bacteria, fungi and viruses. It has been found that the nano size enhances the performances of chitins and chitosans in all cases considered, with no exceptions. Biotechnological approaches will boost the applications of the said safe, eco-friendly and benign nanomaterials not only in these fields, but also for biosensors and in targeted drug delivery areas.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.