Evidence map›Paper›PMID 25415010›Full record

ReviewBritish dental journal2014

Emerging horizons of salivary diagnostics for periodontal disease.

L Fuentes, M Yakob, D T W Wong

Abstract readReview
PubMed Publisher
In one paragraph

Review in British dental journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Genomic Medicine in Canine Periodontal Disease: A Systematic Review.Animals : an open access journal from MDPI · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Nanomaterials for Tissue Engineering In Dentistry.Nanomaterials (Basel, Switzerland) · 2016
    Review
  11. Nanotechnology in dentistry: prevention, diagnosis, and therapy.International journal of nanomedicine · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

L FuentesCentre for Oral/Head &Neck Oncology Research, University of California, Los Angeles, 73017 CHS, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.
M YakobCentre for Oral/Head &Neck Oncology Research, University of California, Los Angeles, 73017 CHS, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.
D T W WongCentre for Oral/Head &Neck Oncology Research, University of California, Los Angeles, 73017 CHS, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.

Funding

Human Salivary ProteomeU01DE016275 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WONG, DAVID T · 2004 to 2007
$5.5M
Salivary Biomarkers for Sjogren's Syndrome Detection-Definitive ValidationU01DE017593 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WONG, DAVID T · 2011 to 2014
$4.3M
Salivary Biomarkers for Early Oral Cancer DetectionR01DE017170 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WONG, DAVID T · 2008 to 2011
$1.5M
Clinical Utility of Salivary ExRNA Biomarkers for Gastric Cancer DetectionUH2TR000923 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WONG, DAVID T · 2013 to 2014
$996k
Collection, Stabilization and Storage of Saliva Samples for Cancer ResearchR21CA126733 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WONG, DAVID T · 2008 to 2009
$381k
NCATS NIH HHS UH2 TR000923NCI NIH HHS R21 CA0126733NIDCR NIH HHS R01 DE017170NIDCR NIH HHS U01 DE016275NIDCR NIH HHS U01 DE017593
6 · The paper itself

Abstract

The field of salivary diagnostics to allow risk determination for periodontal diseases is advancing. New technologies in proteomics, genomics and nanotechnologies have continued the discovery of discriminatory periodontal disease biomarkers. This review briefly overviews biomarker studies that have been completed in saliva for the detection of periodontal disease since 2010. Disease specific biomarkers could be used in risk determination, treatment planning and disease progression. Currently, diagnostic tests are commercially available, and the development of point-of-care tests is expanding. Even though challenges remain, salivary diagnostics for periodontal disease is promising and could facilitate the diagnostics and treatment in a clinical practice by dental practitioners.

Indexed as

BiomarkersHumansPeriodontal DiseasesSalivaBiomarkers

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.