Evidence map›Paper›PMID 25414570›Full record

ArticleWSEAS transactions on mathematics2013

Network Theory Tools for RNA Modeling.

Namhee Kim, Louis Petingi, Tamar Schlick

Abstract read
In one paragraph

Article in WSEAS transactions on mathematics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Prediction of pyrazinamide resistance inJAC-antimicrobial resistance · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Adventures with RNA graphs.Methods (San Diego, Calif.) · 2018
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Graph-based sampling for approximating global helical topologies of RNA.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Namhee KimNew York University Department of Chemistry Courant Institute of Mathematical Sciences 251 Mercer Street New York, NY 10012, USA.
Louis PetingiCollege of Staten Island City University of New York Department of Computer Science 2800 Victory Boulevard Staten Island, NY 10314, USA louis.petingi@csi.cuny.edu.
Tamar SchlickNew York University Department of Chemistry Courant Institute of Mathematical Sciences 251 Mercer Street New York, NY 10012, USA schlick@nyu.edu.

Funding

Modeling RNA Tertiary Structure Folding by a Hierarchical FrameworkR01GM100469 · NIGMS · NEW YORK UNIVERSITY · PI SCHLICK, TAMAR · 2011 to 2014
$1.5M
Computational studies of in vitro selection of RNAsR01GM081410 · NIGMS · NEW YORK UNIVERSITY · PI SCHLICK, TAMAR · 2009 to 2012
$1.2M
NIGMS NIH HHS R01 GM081410NIGMS NIH HHS R01 GM100469
6 · The paper itself

Abstract

An introduction into the usage of graph or network theory tools for the study of RNA molecules is presented. By using vertices and edges to define RNA secondary structures as tree and dual graphs, we can enumerate, predict, and design RNA topologies. Graph connectivity and associated Laplacian eigenvalues relate to biological properties of RNA and help understand RNA motifs as well as build, by computational design, various RNA target structures. Importantly, graph theoretical representations of RNAs reduce drastically the conformational space size and therefore simplify modeling and prediction tasks. Ongoing challenges remain regarding general RNA design, representation of RNA pseudoknots, and tertiary structure prediction. Thus, developments in network theory may help advance RNA biology.

Indexed as

In Vitro SelectionNetwork TheoryRNA-As-GraphsRNA Prediction

Identifiers

PMID25414570
PMCPMC4235620

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.