Evidence map›Paper›PMID 25414415›Full record

ReviewThe Journal of infectious diseases2014

Vaginal microbiota and sexually transmitted infections that may influence transmission of cell-associated HIV.

Richard A Cone

Abstract readReview
In one paragraph

Review in The Journal of infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
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  11. Article
  12. Review
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  14. Article
  15. Review
  16. Microbiome as an Immunological Modifier.Methods in molecular biology (Clifton, N.J.) · 2020
    Article
  17. Article
  18. Article
  19. Vaginal microbiota and susceptibility to HIV.AIDS (London, England) · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Richard A ConeDepartment of Biophysics, Johns Hopkins University, Baltimore, Maryland.

Funding

Vaginal mAB Delivery SystemsU19AI096398 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ANDERSON, DEBORAH J, MOENCH, THOMAS RAY · 2011 to 2016
$15.0M
NIAID NIH HHS 1U19AI096398NIAID NIH HHS U19 AI096398
6 · The paper itself

Abstract

Vaginal microbiota and sexually transmitted infections (STIs) are likely to influence the transmission of cell-associated human immunodeficiency virus (HIV). Lactic acid produced by Lactobacillus-dominated microbiota (Nugent score 0-3) will likely inhibit transmission, especially female-to-male transmission. In contrast, polymicrobial microbiota (Nugent score 4-10), community state types IV-A and IV-B, and STIs will likely increase transmission of cell-associated HIV.

Indexed as

FemaleHIV InfectionsHumansLactic AcidLactobacillusLeukocytesMaleMicrobiotaSexually Transmitted DiseasesVaginaVaginal DiseasesLactic Acidcell-associated HIVinflammatory cytokineslactic acidpolymicrobial microbiota

Identifiers

PMID25414415
PMCPMC4303075

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.