Evidence map›Paper›PMID 25414414›Full record

ReviewThe Journal of infectious diseases2014

Characteristics and quantities of HIV host cells in human genital tract secretions.

Joseph A Politch, Jai Marathe, Deborah J Anderson

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Longitudinal Viral Dynamics in Semen During Early HIV Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Article
  10. Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joseph A PolitchDepartment of Obstetrics and Gynecology.
Jai MaratheDepartment of Medicine, Boston University School of Medicine, Massachusetts.
Deborah J AndersonDepartment of Obstetrics and Gynecology Department of Medicine, Boston University School of Medicine, Massachusetts.
Boston University · US

Funding

Vaginal mAB Delivery SystemsU19AI096398 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ANDERSON, DEBORAH J, MOENCH, THOMAS RAY · 2011 to 2016
$15.0M
NIAID NIH HHS U19 AI096398
6 · The paper itself

Abstract

Human immunodeficiency virus (HIV)-infected leukocytes have been detected in genital secretions from HIV-infected men and women and may play an important role in the sexual transmission of HIV. However, they have been largely overlooked in studies on mechanisms of HIV transmission and in the design and testing of HIV vaccine and microbicide candidates. This article describes the characteristics and quantities of leukocytes in male and female genital secretions under various conditions and also reviews evidence for the involvement of HIV-infected cells in both horizontal and vertical cell-associated HIV transmission. Additional research is needed in this area to better target HIV prevention strategies.

Indexed as

FemaleGenital Diseases, FemaleGenital Diseases, MaleGenitalia, FemaleGenitalia, MaleHIVHIV InfectionsHumansInfectious Disease Transmission, VerticalLeukocytesMaleSemenAIDScell-associatedHIVinfected leukocytesmucosalrectumsementransmissionvagina

Identifiers

PMID25414414
PMCPMC4303079
OpenAlexW2020549361

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.