ReviewThe Journal of infectious diseases2014
Characteristics and quantities of HIV host cells in human genital tract secretions.
Review in The Journal of infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- Mucosal application of the broadly neutralizing antibody 10-1074 protects macaques from cell-associated SHIV vaginal exposure.Nature communications · 2023Article
- Article
- Experimental Models to Study HIV Latency Reversal from Male Genital Myeloid Cells.Methods in molecular biology (Clifton, N.J.) · 2022Article
- An Efficient Microwave-Mediated Synthesis of Hexavalent Sialic Acid Sulfoglycodendrimers as Potential Anti-HIV Agents.ACS applied polymer materials · 2020Article
- The importance of semen leukocytes in HIV-1 transmission and the development of prevention strategies.Human vaccines & immunotherapeutics · 2020Review
- Exogenous oestrogen inhibits genital transmission of cell-associated HIV-1 in DMPA-treated humanized mice.Journal of the International AIDS Society · 2018Article
- Systemic and topical use of monoclonal antibodies to prevent the sexual transmission of HIV.AIDS (London, England) · 2017Review
- JAK-STAT Signaling Pathways and Inhibitors Affect Reversion of Envelope-Mutated HIV-1.Journal of virology · 2017Article
- Longitudinal Viral Dynamics in Semen During Early HIV Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017Article
- Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Human vaginal fluid contains exosomes that have an inhibitory effect on an early step of the HIV-1 life cycle.AIDS (London, England) · 2016Article
- Monocytes but Not Lymphocytes Carrying HIV-1 on Their Surface Transmit Infection to Human Tissue Ex Vivo.Journal of virology · 2016Article
- HIV-1 is undetectable in preejaculatory secretions from HIV-1-infected men on suppressive HAART.AIDS (London, England) · 2016Article
- HIV-1 cellular and tissue replication patterns in infected humanized mice.Scientific reports · 2016Article
- Chlamydia trachomatis Infection of Endocervical Epithelial Cells Enhances Early HIV Transmission Events.PloS one · 2016Article
- Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis.Frontiers in physiology · 2015Review
- Modeling mucosal cell-associated HIV type 1 transmission in vitro.The Journal of infectious diseases · 2014Review
- Cell-associated HIV mucosal transmission: the neglected pathway.The Journal of infectious diseases · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Human immunodeficiency virus (HIV)-infected leukocytes have been detected in genital secretions from HIV-infected men and women and may play an important role in the sexual transmission of HIV. However, they have been largely overlooked in studies on mechanisms of HIV transmission and in the design and testing of HIV vaccine and microbicide candidates. This article describes the characteristics and quantities of leukocytes in male and female genital secretions under various conditions and also reviews evidence for the involvement of HIV-infected cells in both horizontal and vertical cell-associated HIV transmission. Additional research is needed in this area to better target HIV prevention strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.