ReviewCold Spring Harbor perspectives in biology2014
Allergic inflammation--innately homeostatic.
Review in Cold Spring Harbor perspectives in biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- Brain-immune interactions generate pathogen-specific sickness states.bioRxiv : the preprint server for biology · 2025Article
- Article
- Regulatory T cells in allergic inflammation.Seminars in immunology · 2023Review
- Article
- Article
- Chronic allergy signaling: is it all stressed-out mitochondria?Faculty reviews · 2022Review
- Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation.Immunity · 2021Article
- Article
- Acupoint application inhibits nerve growth factor and attenuates allergic inflammation in allergic rhinitis model rats.Journal of inflammation (London, England) · 2020Article
- Clinical Applications of System Regulation Medicine.Open access Macedonian journal of medical sciences · 2019Review
- Vagus nerve stimulation dampens intestinal inflammation in a murine model of experimental food allergy.Allergy · 2019Article
- Article
- Elaeocarpusin Inhibits Mast Cell-Mediated Allergic Inflammation.Frontiers in pharmacology · 2018Article
- Cholinergic Modulation of Type 2 Immune Responses.Frontiers in immunology · 2017Review
- The Mucosal Immune System and Its Regulation by Autophagy.Frontiers in immunology · 2016Review
- Type 2 responses at the interface between immunity and fat metabolism.Current opinion in immunology · 2015Review
- MicroRNA regulation of allergic inflammation and asthma.Current opinion in immunology · 2015Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Allergic inflammation is associated closely with parasite infection but also asthma and other common allergic diseases. Despite the engagement of similar immunologic pathways, parasitized individuals often show no outward manifestations of allergic disease. In this perspective, we present the thesis that allergic inflammatory responses play a primary role in regulating circadian and environmental inputs involved with tissue homeostasis and metabolic needs. Parasites feed into these pathways and thus engage allergic inflammation to sustain aspects of the parasitic life cycle. In response to parasite infection, an adaptive and regulated immune response is layered on the host effector response, but in the setting of allergy, the effector response remains unregulated, thus leading to the cardinal features of disease. Further understanding of the homeostatic pressures driving allergic inflammation holds promise to further our understanding of human health and the treatment of these common afflictions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.