Evidence map›Paper›PMID 25413735›Full record

ArticleClinical rheumatology2015

Remission of rheumatoid arthritis and potential determinants: a national multi-center cross-sectional survey.

Guan-Ying Wang, Sa-Li Zhang, Xiu-Ru Wang, Min Feng, Chun Li, Yuan An, Xiao-Feng Li, Li-Zhi Wang, Cai-Hong Wang, Yong-Fu Wang and 60 more

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. [Molecular mechanism ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Review
  10. Salvianolic Acid B Suppresses Inflammatory Mediator Levels by Downregulating NF-κB in a Rat Model of Rheumatoid Arthritis.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  11. Observational
  12. Article
  13. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

70 authors at 20 institutions in 1 country.

Guan-Ying WangDepartment of Rheumatology and Immunology, Peking University People's Hospital, No.11 Xizhimen South Street, Beijing, 100044, China.
Sa-Li Zhang
Xiu-Ru Wang
Min Feng
Chun Li
Yuan An
Xiao-Feng Li
Li-Zhi Wang
Cai-Hong Wang
Yong-Fu Wang
Rong Yang
Hui-Ming Yan
Guo-Chun Wang
Xin Lu
Xia Liu
Ping Zhu
Li-Na Chen
Hong-Tao Jin
Jin-Ting Liu
Hui-Fang Guo
Hai-Ying Chen
Jian-Li Xie
Ping Wei
Jun-Xiang Wang
Xiang-Yuan Liu
Lin Sun
Liu-Fu Cui
Rong Shu
Bai-Lu Liu
Ping Yu
Zhuo-Li Zhang
Guang-Tao Li
Zhen-Bin Li
Jing Yang
Jun-Fang Li
Bin Jia
Feng-Xiao Zhang
Jie-Mei Tao
Jin-Ying Lin
Mei-Qiu Wei
Xiao-Min Liu
Dan Ke
Shao-Xian Hu
Cong Ye
Shu-Ling Han
Xiu-Yan Yang
Hao Li
Ci-Bo Huang
Ming Gao
Bei Lai
Yong-Jing Cheng
Xing-Fu Li
Li-Jun Song
Xiao-Xia Yu
Ai-Xue Wang
Li-Jun Wu
Yan-Hua Wang
Lan He
Wen-Wen Sun
Lu Gong
Xiao-Yuan Wang
Yi Wang
Yi Zhao
Xiao-Xia Li
Yan Wang
Yan Zhang
Yin Su
Chun-Fang Zhang
Rong Mu
Zhan-Guo Li
Peking University · CNHebei Medical University · CNBeijing Hospital · CNKailuan General Hospital · CNLanzhou University · CNBaotou Medical College · CNPeking University People's Hospital · CNBeijing Xuanwu Traditional Chinese Medicine Hospital · CNBethune International Peace Hospital · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNHandan College · CNHospital of Hebei Province · CNHuazhong University of Science and Technology · CNPeople's Hospital of Xinjiang Uygur Autonomous Region · CNQilu Hospital of Shandong University · CNShanxi Medical University · CNShunyi Hospital of Beijing Traditional Chinese Medicine Hospital · CNThe People's Hospital of Guangxi Zhuang Autonomous Region · CNTianjin Medical University General Hospital · CNAir Force Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to investigate the remission rate of rheumatoid arthritis (RA) in China and identify its potential determinants. A multi-center cross-sectional study was conducted from July 2009 to January 2012. Data were collected by face-to-face interviews of the rheumatology outpatients in 28 tertiary hospitals in China. The remission rates were calculated in 486 RA patients according to different definitions of remission: the Disease Activity Score in 28 joints (DAS28), the Simplified Disease Activity Index (SDAI), the Clinical Disease Activity Index (CDAI), and the American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) Boolean definition. Potential determinants of RA remission were assessed by univariate and multivariate analyses. The remission rates of RA from this multi-center cohort were 8.6% (DAS28), 8.4% (SDAI), 8.2% (CDAI), and 6.8% (Boolean), respectively. Favorable factors associated with remission were: low Health Assessment Questionnaire (HAQ) score, absence of rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP), and treatment of methotrexate (MTX) and hydroxychloroquine (HCQ). Younger age was also predictive for the DAS28 and the Boolean remission. Multivariate analyses revealed a low HAQ score, the absence of anti-CCP, and the treatment with HCQ as independent determinants of remission. The clinical remission rate of RA patients was low in China. A low HAQ score, the absence of anti-CCP, and HCQ were significant independent determinants for RA remission.

Indexed as

Remission InductionAdultAgedAntirheumatic AgentsArthritis, RheumatoidChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedRisk FactorsSeverity of Illness IndexTreatment OutcomeAntirheumatic Agents

Identifiers

PMID25413735
OpenAlexW2030948266

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.