ArticleScientific reports2014
Tree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Advances in the Comprehensive Tree Shrew Brain Atlas.Biomolecules · 2026Review
- High-throughput markerless pose estimation and home-cage activity analysis of tree shrew using deep learning.Animal models and experimental medicine · 2025Article
- Tree shrew as a new animal model for musculoskeletal disorders and aging.Bone research · 2025Article
- Whole-genome DNA methylomes of tree shrew brains reveal conserved and divergent roles of DNA methylation on sex chromosome regulation.BMC biology · 2024Article
- Study of tree shrew biology and models: A booming and prosperous field for biomedical research.Zoological research · 2024Review
- Whole-genome DNA methylomes of Tree shrew brains reveal conserved and divergent roles of DNA methylation on sex chromosome regulation.bioRxiv : the preprint server for biology · 2024Article
- Advances in viral encephalitis: Viral transmission, host immunity, and experimental animal models.Zoological research · 2023Review
- Deficiency of primate-specific SSX1 induced asthenoteratozoospermia in infertile men and cynomolgus monkey and tree shrew models.American journal of human genetics · 2023Article
- Comprehensive annotation of the Chinese tree shrew genome by large-scale RNA sequencing and long-read isoform sequencing.Zoological research · 2021Article
- Tree Shrew Cells Transduced with Human CD4 and CCR5 Support Early Steps of HIV-1 Replication, but Viral Infectivity Is Restricted by APOBEC3.Journal of virology · 2021Article
- Genome-wide DNA methylome and whole-transcriptome landscapes of spontaneous intraductal papilloma in tree shrews.Annals of translational medicine · 2021Article
- The Tree Shrew as a Model for Cancer Research.Frontiers in oncology · 2021Review
- HSV-1 infection and pathogenesis in the tree shrew eye following corneal inoculation.Journal of neurovirology · 2020Article
- Chromosomal level assembly and population sequencing of the Chinese tree shrew genome.Zoological research · 2019Article
- Construction of complete Tupaia belangeri transcriptome database by whole-genome and comprehensive RNA sequencing.Scientific reports · 2019Article
- Molecular mechanism of the tree shrew's insensitivity to spiciness.PLoS biology · 2018Article
- Tree shrew neural stem cell transplantation promotes functional recovery of tree shrews with a hemi‑sectioned spinal cord injury by upregulating nerve growth factor expression.International journal of molecular medicine · 2018Article
- Comparison of the properties of neural stem cells of the hippocampus in the tree shrew and rat in vitro.Molecular medicine reports · 2018Article
- Characterization of tree shrew (Tupaia belangeri) interleukin-6 and its expression pattern in response to exogenous challenge.International journal of molecular medicine · 2017Article
- Creating animal models, why not use the Chinese tree shrew (Zoological research · 2017Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The tree shrew (Tupaia belangeri) is a small mammal with a close relationship to primates and it has been proposed as an alternative experimental animal to primates in biomedical research. The recent release of a high-quality Chinese tree shrew genome enables more researchers to use this species as the model animal in their studies. With the aim to making the access to an extensively annotated genome database straightforward and easy, we have created the Tree shrew Database (TreeshrewDB). This is a web-based platform that integrates the currently available data from the tree shrew genome, including an updated gene set, with a systematic functional annotation and a mRNA expression pattern. In addition, to assist with automatic gene sequence analysis, we have integrated the common programs Blast, Muscle, GBrowse, GeneWise and codeml, into TreeshrewDB. We have also developed a pipeline for the analysis of positive selection. The user-friendly interface of TreeshrewDB, which is available at http://www.treeshrewdb.org, will undoubtedly help in many areas of biological research into the tree shrew.
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