ArticlePhysiological reports2014
Infrared thermography in the detection of brown adipose tissue in humans.
Article in Physiological reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 97 citations in OpenAlex.
- A systematic review on the role of infrared thermography in the Brown adipose tissue assessment.Reviews in endocrine & metabolic disorders · 2020Pooled it
- Infrared Thermography for Estimating Supraclavicular Skin Temperature and BAT Activity in Humans: A Systematic Review.Obesity (Silver Spring, Md.) · 2019Pooled it
- Single intake of matcha increases brown adipose tissue activity in young women with low thermogenesis.Physiological reports · 2026Trial
- Effects of boysenberry on postprandial energy metabolism in healthy adults: A randomized controlled crossover trial.PloS one · 2025Trial
- Preliminary study on the effects of boysenberry juice intake on brown adipose tissue activity in healthy adults.Scientific reports · 2024Trial
- The Infrared Thermography Toolbox: An Open-access Semi-automated Segmentation Tool for Extracting Skin Temperatures in the Thoracic Region including Supraclavicular Brown Adipose Tissue.Journal of medical systems · 2022Trial
- Effect of Liothyronine Treatment on Dermal Temperature and Activation of Brown Adipose Tissue in Female Hypothyroid Patients: A Randomized Crossover Study.Frontiers in endocrinology · 2021Trial
- Measurement of Brown Adipose Tissue Activity Using Microwave Radiometry andJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2018Trial
- A new method of infrared thermography for quantification of brown adipose tissue activation in healthy adults (TACTICAL): a randomized trial.The journal of physiological sciences : JPS · 2017Trial
- Glucocorticoids Acutely Increase Brown Adipose Tissue Activity in Humans, Revealing Species-Specific Differences in UCP-1 Regulation.Cell metabolism · 2016Trial
- EAT Thickness and BAT-Related Thermogenesis: Dual Imaging Phenotypes Associated with Hepatic Steatosis Severity in MASLD.Diagnostics (Basel, Switzerland) · 2026Article
- Clinical Use of Infrared Thermography: Where Are We and Where Are We Going.Medicina (Kaunas, Lithuania) · 2026Article
- Investigation of the relationship between BAT activity and thermal comfort under short-term cold temperature exposure.Scientific reports · 2025Article
- Thermogenic Activation of Adipose Tissue by Caffeine During Strenuous Exercising and Recovery: A Double-Blind Crossover Study.Metabolites · 2025Article
- Brown fat thermogenesis and cold adaptation in humans.Journal of physiological anthropology · 2025Review
- Infrared thermography unveiled the variation of brown adipose tissue thermogenesis among East Asian adults.Physiological reports · 2025Article
- When the cold gets under your skin: Evidence for brown adipose tissue activity in Samoan adults.American journal of biological anthropology · 2024Article
- Brown fat detection by infrared thermography-An invaluable research methodology with noteworthy uncertainties confirmed by a mathematical proof.Endocrinology, diabetes & metabolism · 2023Article
- Cold-induced Conversion of Connective Tissue Skeleton in Brown Adipose Tissues.Acta histochemica et cytochemica · 2021Article
- Molecular Imaging of Brown Adipose Tissue Mass.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PET-CT using (18)F-FDG is employed for detecting brown adipose tissue (BAT) in humans. Alternative methods are needed because of the radiation and cost of PET-CT imaging. The aim was to evaluate the accuracy of infrared thermography (IRT) in detecting human BAT benchmarked to PET-CT imaging. Seventeen individuals underwent a total of 29 PET-CT scans, 12 of whom were studied twice, after 2 h of cold stimulation at 19°C, in parallel with measurement of skin temperatures overlying the supraclavicular (SCV) fossa and the lateral upper chest (control), before and after cold stimulation. Of the 29 scans, 20 were BAT positive after cold stimulation. The mean left SCV temperature tended to be higher in the BAT-positive group before and during cooling. It was significantly higher (P = 0.04) than the temperature of the control area, which fell significantly during cooling in the BAT-positive (-1.2 ± 0.3°C, P = 0.002) but not in the negative (-0.2 ± 0.4°C) group. The temperature difference (Δtemp) between left SCV and chest increased during cooling in the BAT-positive (1.2 ± 0.2 to 2.0 ± 0.3°C, P < 0.002) but not in the negative group (0.6 ± 0.1 to 0.7 ± 0.1°C). A Δtemp of 0.9°C conferred a positive predictive value of 85% for SCV BAT, superior to that of SCV temperature. The findings were similar on the right. In conclusion, the Δtemp is significantly and consistently greater in BAT-positive subjects. The Δtemp quantified by IRT after 2-h cooling shows promise as a noninvasive convenient technique for studying SCV BAT function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.