Evidence map›Paper›PMID 25413264›Full record

Trial reportJournal of clinical hypertension (Greenwich, Conn.)2015

Reinforcing adherence to antihypertensive medications.

Nancy M Petry, Sheila M Alessi, Shannon Byrne, William B White

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical hypertension (Greenwich, Conn.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. A Randomized Trial of Adjunct mHealth Abstinence Reinforcement With Transdermal Nicotine and Counseling for Smoking Cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Trial
  5. Review
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  7. Article
  8. Article
  9. Article
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  12. Contingency management treatment for substance use disorders: How far has it come, and where does it need to go?Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2017
    Review
  13. Article
  14. Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nancy M PetryCalhoun Cardiology Center and Department of Medicine, University of Connecticut School of Medicine, Farmington, CT.
Sheila M Alessi
Shannon Byrne
William B White
University of Connecticut · US

Funding

TSF to enhance treatment of cocaine dependenceP50DA009241 · NIDA · YALE UNIVERSITY · PI KOBER, HEDY · 1994 to 2018
$40.5M
ZONISAMIDE VERSUS PLACEBOM01RR006192 · NCRR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LAURENCIN, CATO T. · 1994 to 2008
$22.1M
Vulnerabilities for coping-related drinking among post-college young adultsP60AA003510 · NIAAA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI BAUER, LANCE O. · 2008 to 2017
$17.5M
Intensive Blood Pressure Reduction to Lessen Functional DeclineR01AG022092 · NIA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI WHITE, WILLIAM BARRY, WOLFSON, LESLIE · 2004 to 2017
$6.6M
ART Adherence and Secondary Prevention of HIVR01HD075630 · NICHD · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI RASH, CARLA J · 2012 to 2016
$3.3M
POST-DOCTORAL TRAINING PROGRAM IN ALCOHOL STUDIEST32AA007290 · NIAAA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI SHEILA MARIE ALESSI · 1985 to 2026
$3.2M
Reinforcing Exercise in Cocaine AbusersR01DA027615 · NIDA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI PETRY, NANCY M · 2009 to 2013
$3.2M
Contingency Management for Initiating Smoking AbstinenceR01DA024667 · NIDA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI WHITE, WILLIAM BARRY · 2008 to 2012
$2.8M
A Reinforcement Approach to Improve Diabetes ManagementDP3DK097705 · NIDDK · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI PETRY, NANCY M · 2012 to 2012
$2.2M
Recovery Enhancement With Awards Enhancement With Awards Research Dissemination (P30DA023918 · NIDA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI PETRY, NANCY M · 2009 to 2010
$1.8M
NCRR NIH HHS M01 RR006192NIAAA NIH HHS P60 AA003510NIAAA NIH HHS T32 AA007290NIAAA NIH HHS T32-AA07290NIA NIH HHS R01-AG02209NIA NIH HHS R01 AG022092NICHD NIH HHS R01 HD075630NICHD NIH HHS R01-HD075630NIDA NIH HHS P30 DA023918NIDA NIH HHS P30-DA023918NIDA NIH HHS P50 DA009241NIDA NIH HHS P50-DA09241NIDA NIH HHS R01 DA024667NIDA NIH HHS R01-DA024667NIDA NIH HHS R01 DA027615NIDA NIH HHS R01-DA027615NIDDK NIH HHS DP3 DK097705
6 · The paper itself

Abstract

This pilot study evaluated a reinforcement intervention to improve adherence to antihypertensive therapy. Twenty-nine participants were randomized to standard care or standard care plus financial reinforcement for 12 weeks. Participants in the reinforcement group received a cell phone to self-record videos of adherence, for which they earned rewards. These participants sent videos demonstrating on-time adherence 97.8% of the time. Pill count adherence differed significantly between the groups during treatment, with 98.8%±1.5% of pills taken during treatment in the reinforcement condition vs 92.6%±9.2% in standard care (P<.002). Benefits persisted throughout a 3-month follow-up, with 93.8%±9.3% vs 78.0%±18.5% of pills taken (P<.001). Pill counts correlated significantly (P<.001) with self-reports of adherence, which also differed between groups over time (P<.01). Systolic blood pressure decreased modestly over time in participants overall (P<.01) but without significant time-by-group effects. These results suggest that reinforcing medication adherence via cellular phone technology and financial reinforcement holds potential to improve adherence.

Indexed as

Reinforcement, PsychologyAdultAntihypertensive AgentsBlood PressureCell PhoneFemaleFollow-Up StudiesHumansHypertensionMaleMedication AdherenceMiddle AgedPatient CompliancePilot ProjectsSelf ReportTreatment OutcomeAntihypertensive Agents

Identifiers

PMID25413264
PMCPMC4293311
OpenAlexW2058400556

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.