ReviewJournal of industrial microbiology & biotechnology2015
Metabolic engineering of strains: from industrial-scale to lab-scale chemical production.
Review in Journal of industrial microbiology & biotechnology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 61 citations in OpenAlex.
- Auxotrophy-based curation improves the consensus genome-scale metabolic model of yeast.Synthetic and systems biotechnology · 2024Article
- Integrated omics of Saccharomyces cerevisiae CENPK2-1C reveals pleiotropic drug resistance and lipidomic adaptations to cannabidiol.NPJ systems biology and applications · 2024Article
- State-of-the-art in engineering small molecule biosensors and their applications in metabolic engineering.SLAS technology · 2024Review
- Conversion of Polyethylenes into Fungal Secondary Metabolites.Angewandte Chemie (International ed. in English) · 2023Article
- Metabolic Dynamics inACS synthetic biology · 2021Article
- From Data Mining ofMicroorganisms · 2021Article
- Metabolic engineering of microbial cell factories for production of nutraceuticals.Microbial cell factories · 2019Review
- A Review of the Microbial Production of Bioactive Natural Products and Biologics.Frontiers in microbiology · 2019Review
- Expanding beyond canonical metabolism: Interfacing alternative elements, synthetic biology, and metabolic engineering.Synthetic and systems biotechnology · 2018Review
- RNA-aptamers-in-droplets (RAPID) high-throughput screening for secretory phenotypes.Nature communications · 2017Article
- Coupling gene regulatory patterns to bioprocess conditions to optimize synthetic metabolic modules for improved sesquiterpene production in yeast.Biotechnology for biofuels · 2017Article
- Exploiting members of the BAHD acyltransferase family to synthesize multiple hydroxycinnamate and benzoate conjugates in yeast.Microbial cell factories · 2016Article
- Yeast metabolic chassis designs for diverse biotechnological products.Scientific reports · 2016Article
- Combinatorial metabolic pathway assembly in the yeast genome with RNA-guided Cas9.Journal of industrial microbiology & biotechnology · 2016Article
- Assessing Inhalation Exposures Associated with Contamination Events in Water Distribution Systems.PloS one · 2016Article
- Sequence Assembly of Yarrowia lipolytica Strain W29/CLIB89 Shows Transposable Element Diversity.PloS one · 2016Article
- Improvement of lactic acid production in Saccharomyces cerevisiae by a deletion of ssb1.Journal of industrial microbiology & biotechnology · 2016Article
- Synthetic biology for pharmaceutical drug discovery.Drug design, development and therapy · 2015Review
- Lean-proteome strains - next step in metabolic engineering.Frontiers in bioengineering and biotechnology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A plethora of successful metabolic engineering case studies have been published over the past several decades. Here, we highlight a collection of microbially produced chemicals using a historical framework, starting with titers ranging from industrial scale (more than 50 g/L), to medium-scale (5-50 g/L), and lab-scale (0-5 g/L). Although engineered Escherichia coli and Saccharomyces cerevisiae emerge as prominent hosts in the literature as a result of well-developed genetic engineering tools, several novel native-producing strains are gaining attention. This review catalogs the current progress of metabolic engineering towards production of compounds such as acids, alcohols, amino acids, natural organic compounds, and others.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.