ArticleJournal of gastrointestinal cancer2015
The descriptive epidemiology of gastric cancer in Central America and comparison with United States Hispanic populations.
Article in Journal of gastrointestinal cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- Safety and Efficacy of Eflornithine in Patients with Gastric Precancerous Lesions: A Double-Blinded, Randomized Clinical Trial.Cancer prevention research (Philadelphia, Pa.) · 2026Trial
- Genetic heterogeneity and key driver mutations in the preneoplastic and earliest stages of gastric cancer.Gastroenterology report · 2025Article
- Gastric cancer in Central America: a scoping review.Ecancermedicalscience · 2025Review
- High Incidence of Gastric Cancer in El Salvador: A National Multisectorial Study during 2000 to 2014.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Facilitators of and barriers to gastric cancer and precursor diagnosis among South Texas residents: Social determinants of health.Cancer medicine · 2024Article
- Wood cookstove use is associated with gastric cancer in Central America and mediated by host genetics.Scientific reports · 2023Article
- Racial/ethnic disparities in gastric cancer: A 15-year population-based analysis.Cancer medicine · 2023Article
- Somatic Mutational Landscape in Mexican Patients:International journal of molecular sciences · 2022Article
- Upper Gastrointestinal Cancer: Delays in Diagnosis and Treatment Caused by Barriers to Healthcare in the Latino Community.Gastroenterology research · 2022Article
- Western Honduras Copán Population-Based Cancer Registry: Initial Estimates and a Model for Rural Central America.JCO global oncology · 2021Article
- Gastric adenocarcinoma burden and late-stage diagnosis in Latino and non-Latino populations in the United States and Texas, during 2004-2016: A multilevel analysis.Cancer medicine · 2021Article
- Helicobacter pylori infection causes both protective and deleterious effects in human health and disease.Genes and immunity · 2021Review
- Risk Factors and Incidence of Gastric Cancer After Detection of Helicobacter pylori Infection: A Large Cohort Study.Gastroenterology · 2020Article
- Helicobacter pylori antimicrobial resistance and antibiotic consumption in the low-resource Central America setting.Helicobacter · 2019Article
- Racial/ethnic differences in survival among gastric cancer patients in california.Cancer causes & control : CCC · 2019Article
- Geospatial analyses identify regional hot spots of diffuse gastric cancer in rural Central America.BMC cancer · 2019Article
- Gastric cancer in Alaska Native people: A cancer health disparity.World journal of gastroenterology · 2018Article
- Can a gastric cancer risk survey identify high-risk patients for endoscopic screening? A pilot study.The Journal of surgical research · 2018Article
- Observational
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
Abstract
purposeThe aims of this study were to delineate the epidemiology of gastric adenocarcinoma in Central America and contrast it with Hispanic-Latino populations in the USA.
methodsPublished literature and Central America Ministry of Health databases were used as primary data sources, including national, population-based, and hospital-based registries. US data was obtained from the National Cancer Institute (NCI)-Epidemiology End Results Program (SEER) registry. Incident gastric adenocarcinoma cases were analyzed for available data between 1985 and 2011, including demographic variables and pathology information.
resultsIn Central America, 19,741 incident gastric adenocarcinomas were identified. Two thirds of the cases were male, 20.5 % were under age 55, and 58.5 %were from rural areas. In the SEER database (n = 7871), 57.8 % were male and 28.9 % were under age 55. Among the US Hispanics born in Central America with gastric cancer (n = 1210), 50.3 % of cases were male and 38.1 % were under age 55. Non-cardia gastric cancer was more common in Central America (83.3 %), among US Hispanics (80.2 %), and Hispanics born in Central America (86.3 %). Cancers of the antrum were more common in Central America (73.6 %), whereas cancers of the corpus were slightly more common among US Hispanics (54.0 %). Adenocarcinoma of the diffuse subtype was relatively common, both in Central America (35.7 %) and US Hispanics (69.5 %), although Lauren classification was reported in only 50 % of cases.
conclusionsA significant burden of gastric adenocarcinoma is observed in Central America based upon limited available data. Differences are noted between Central America and US Hispanics. Strengthening population-based registries is needed for improved cancer control in Central America, which may have implications for the growing US Hispanic population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.