Evidence map›Paper›PMID 25412724›Full record

Trial reportJournal of the International Association of Providers of AIDS Care

A Peer-Led HIV Medication Adherence Intervention Targeting Adults Linked to Medical Care but without a Suppressed Viral Load.

Maithe Enriquez, An-Lin Cheng, Julie Banderas, Rose Farnan, Keyna Chertoff, Deana Hayes, Gerry Ortego, Jose Moreno, Jane Peterson, David McKinsey

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  6. Peer Navigation for Smoking Cessation in People With HIV Who Smoke: A Pilot Randomized Controlled Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maithe EnriquezSinclair School of Nursing, University of Missouri, Columbia, MO, USA enriquezm@missouri.edu.
An-Lin ChengSchool of Nursing, School of Medicine, University of Missouri-Kansas City, Kansas City, MO, USA.
Julie BanderasSchool of Nursing, School of Medicine, University of Missouri-Kansas City, Kansas City, MO, USA.
Rose FarnanInfectious Disease Clinic, Truman Medical Center, Hospital Hill, Kansas City, MO, USA.
Keyna ChertoffSchool of Nursing, School of Medicine, University of Missouri-Kansas City, Kansas City, MO, USA.
Deana HayesInfectious Disease Clinic, Truman Medical Center, Hospital Hill, Kansas City, MO, USA.
Gerry OrtegoInfectious Disease Clinic, Truman Medical Center, Hospital Hill, Kansas City, MO, USA.
Jose MorenoSchool of Nursing, School of Medicine, University of Missouri-Kansas City, Kansas City, MO, USA.
Jane PetersonSchool of Nursing, School of Medicine, University of Missouri-Kansas City, Kansas City, MO, USA.
David McKinseyInfectious Disease Associates, Kansas City, MO, USA.

Funding

Peers keep it real: reaching 100% adherence to HIV treatmentK01NR014409 · NINR · UNIVERSITY OF MISSOURI-COLUMBIA · PI ENRIQUEZ, MAITHE · 2013 to 2015
$276k
NINR NIH HHS K01 NR014409
6 · The paper itself

Abstract

backgroundNon-adherence to antiretroviral (ART) treatment remains a prevalent problem even among the segment of the U.S. HIV population that is 'linked' to medical care.

methodsControlled pilot feasibility study with ART experienced adult patients (n = 20) linked to HIV medical care without suppressed viral load. Patients were randomized to a peer-led HIV medication adherence intervention named `Ready' or a time equivalent `healthy eating' control arm. Lay individuals living with HIV were trained to facilitate `Ready'.

resultsPatients had been prescribed a mean of three prior ART regimens. The group randomized to `Ready' had significantly improved adherence. MEMS and pharmacy refill data correlated with viral load log drop. Higher readiness for healthful behavior change correlated with viral load drop and approached significance.

conclusionA peer-led medication adherence intervention had a positive impact among adults who had experienced repeated non-adherence to HIV treatment. A larger study is needed to examine intervention dissemination and efficacy.

Indexed as

Medication AdherenceAnti-Retroviral AgentsEarly Medical InterventionFemaleHealth BehaviorHIV InfectionsHumansMalePeer GroupPilot ProjectsViral LoadAnti-Retroviral AgentsadherenceHIVinterventionmedicationpeer led

Identifiers

PMID25412724
PMCPMC5677528

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.