Evidence map›Paper›PMID 25412715›Full record

ArticleEye (London, England)2015

Retrospective contralateral study comparing Descemet membrane endothelial keratoplasty with Descemet stripping automated endothelial keratoplasty.

A-K B Maier, E Gundlach, J Gonnermann, M K J Klamann, E Bertelmann, P W Rieck, A M Joussen, N Torun

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Eye (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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  8. Microorganisms · 2025
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  12. Risk factors for intraocular pressure elevation following Descemet membrane endothelial keratoplasty in Asian patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

A-K B MaierDepartment of Ophthalmology, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Charité, Germany.
E GundlachDepartment of Ophthalmology, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Charité, Germany.
J GonnermannDepartment of Ophthalmology, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Charité, Germany.
M K J KlamannDepartment of Ophthalmology, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Charité, Germany.
E BertelmannDepartment of Ophthalmology, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Charité, Germany.
P W RieckEye Clinic am Kapellenberg, Potsdam, Germany.
A M JoussenDepartment of Ophthalmology, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Charité, Germany.
N TorunDepartment of Ophthalmology, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Charité, Germany.
Charité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn this retrospective study, the visual outcomes and postoperative complications after Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet membrane endothelial keratoplasty (DMEK) in the fellow eye were compared. The patient's satisfaction was evaluated.

methodsA retrospective analysis of 10 patients, who underwent DSAEK in one eye and DMEK surgery in their fellow eye, was performed. Intraoperative and postoperative complications were recorded. Visual and refractive outcomes were evaluated, including higher-order aberrations (HOA) and contrast thresholds. A subjective questionnaire was used to evaluate patient satisfaction.

resultsBest-corrected visual acuity (BCVA) was significantly better in DMEK when compared with DSAEK (0.16±0.10 vs 0.45±0.58 logMAR, P=0.043). Contrast threshold was significantly higher after DMEK than after DSAEK (0.49±0.23 vs 0.25±0.18, P=0.043). Post-keratoplasty astigmatism, mean spherical equivalent, and HOA did not differ. Nine out of ten patients preferred the DMEK procedure. Visual outcome (4.80±1.14 vs 4.50±1.58, P=0.257), surgery associated pain and burden (DMEK: 1.30±0.48 vs DSAEK: 1.30±0.48, P=1.0), estimated time for recovery and rehabilitation (27.6±54.0 vs 24.9±54.8 days, P=0.173), and mean patient satisfaction (5.40±0.84 vs 5.00±1.05, P=0.257) were evaluated equally.

conclusionPatient satisfaction reached high, equal values after DMEK and after DSAEK. Nevertheless, patients preferred DMEK, if given a choice. Reasons for the preference may include better uncorrected and BCVA, and especially a better contrast sensitivity.

Indexed as

Patient SatisfactionPostoperative ComplicationsAgedCorneal DiseasesDescemet MembraneDescemet Stripping Endothelial KeratoplastyFemaleHumansMaleRetrospective StudiesSurveys and QuestionnairesVisual Acuity

Identifiers

PMID25412715
PMCPMC4366458
OpenAlexW2047205175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.