Evidence map›Paper›PMID 25412663›Full record

ArticleCell research2014

Producing GM-CSF: a unique T helper subset?

Dietmar Herndler-Brandstetter, Richard A Flavell

Open access · bronzeAbstract readComment
In one paragraph

Article in Cell research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Repositioning TNature immunology · 2021
    Review
  7. Step-by-Step Immune Activation for Suicide Gene Therapy Reinforcement.International journal of molecular sciences · 2021
    Review
  8. Review
  9. Single-cell Analysis of CAR-T Cell Activation Reveals A Mixed TGenomics, proteomics & bioinformatics · 2019
    Article
  10. Article
  11. Article
  12. Article
  13. CCR6Brain, behavior, and immunity · 2017
    Article
  14. T cell responses in the central nervous system.Nature reviews. Immunology · 2017
    Review
  15. Article
  16. A T Cell View of the Bone Marrow.Frontiers in immunology · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dietmar Herndler-BrandstetterDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
Richard A Flavell1] Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA [2] Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA.
Yale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GM-CSF-producing helper T cells have previously been identified to serve a nonredundant function in the initiation of autoimmune inflammation. An article by Sheng et al. recently published by Cell Research now suggests that the differentiation program of GM-CSF-producing cells from naïve CD4 T cells is distinct from that of Th1 and Th17 cells, and is regulated by the IL-7-STAT5 axis.

Indexed as

AnimalsEncephalomyelitis, Autoimmune, ExperimentalGranulocyte-Macrophage Colony-Stimulating FactorSTAT5 Transcription FactorT-Lymphocytes, Helper-InducerGranulocyte-Macrophage Colony-Stimulating FactorSTAT5 Transcription Factor

Identifiers

PMID25412663
PMCPMC4260353
OpenAlexW2003057093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.