ArticleScientific reports2014
The association between romantic relationship status and 5-HT1A gene in young adults.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- Association of the C-1019G (rs6295) Polymorphism of theDiseases (Basel, Switzerland) · 2026Article
- The Molecular Basis of Love.International journal of molecular sciences · 2025Review
- Genetic and epigenetic effects on couple adjustment in context of romantic relationship: A scoping systematic review.Frontiers in genetics · 2023Article
- Genetic, epigenetic and posttranscriptional mechanisms for treatment of major depression: the 5-HT1A receptor gene as a paradigmJournal of psychiatry & neuroscience : JPN · 2019Review
- The Influence of Genetic Variation on Social Disposition, Romantic Relationships and Social Networks: a Replication Study.Adaptive human behavior and physiology · 2018Article
- Health and health risk behaviour of adolescents-Differences according to family structure. Results of the German KiGGS cohort study.PloS one · 2018Article
- Variation in the β-endorphin, oxytocin, and dopamine receptor genes is associated with different dimensions of human sociality.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Genetic Polymorphism of GABRR2 Modulates Individuals' General Cognitive Ability in Healthy Chinese Han People.Cellular and molecular neurobiology · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
What factors determine whether or not a young adult will fall in love? Sociological surveys and psychological studies have shown that non-genetic factors, such as socioeconomic status, external appearance, and personality attributes, are crucial components in romantic relationship formation. Here we demonstrate that genetic variants also contribute to romantic relationship formation. As love-related behaviors are associated with serotonin levels in the brain, this study investigated to what extent a polymorphism (C-1019G, rs6295) of 5-HT1A gene is related to relationship status in 579 Chinese Han people. We found that 50.4% of individuals with the CC genotype and 39.0% with CG/GG genotype were in romantic relationship. Logistic regression analysis indicated that the C-1019G polymorphism was significantly associated with the odds of being single both before and after controlling for socioeconomic status, external appearance, religious beliefs, parenting style, and depressive symptoms. These findings provide, for the first time, direct evidence for the genetic contribution to romantic relationship formation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.