ArticleChest2015
Obesity and weight gain in relation to incidence of sarcoidosis in US black women: data from the Black Women's Health Study.
Article in Chest, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 65 citations in OpenAlex.
- Treatable traits approach for personalised management of sarcoidosis.BMJ open respiratory research · 2026Review
- Soluble CD14 and Lipopolysaccharide-Binding Protein Are Not Superior to Soluble CD25 as Biomarkers for Sarcoidosis.Diagnostics (Basel, Switzerland) · 2026Article
- Sarcoidosis relapse risk factors: a single-centre retrospective cluster analysis.BMJ open respiratory research · 2026Article
- The Impact of Nutritional Status on Survival and Development of Sarcoidosis: A Scoping Review of Current Evidence and Research Gaps.Nutrients · 2026Review
- Sarcoidosis and Risk of Nephrolithiasis in US Black Women: Data from the Black Women's Health Study.CHEST pulmonary · 2025Article
- Incidence, prevalence, and mortality of sarcoidosis in England: a population-based study.The Lancet regional health. Europe · 2025Article
- GWAS identifies genetic loci, lifestyle factors and circulating biomarkers that are risk factors for sarcoidosis.Nature communications · 2025Article
- Phenotypes and Endotypes in Sarcoidosis: Unraveling Prognosis and Disease Course.Biomedicines · 2025Review
- Large-scale analysis highlights obesity as a risk factor for chronic, non-communicable inflammatory diseases.Frontiers in endocrinology · 2025Article
- Phenotyping sarcoidosis: a single institution retrospective analysis.Frontiers in medicine · 2025Article
- The Association Between Sarcoidosis and Malignancy: A Comprehensive Population-Based Cohort Study.Journal of clinical medicine · 2024Article
- Clinical outcomes following hospitalization for COVID-19 in patients with cardiac sarcoidosis in the United States: a propensity-matched analysis from national inpatient sample database from April 2020 to December 2021.Annals of medicine and surgery (2012) · 2024Article
- Role of triglyceride-glucose index in metabolic assessment of sarcoidosis patients.Internal and emergency medicine · 2024Article
- Phenotypes and Serum Biomarkers in Sarcoidosis.Diagnostics (Basel, Switzerland) · 2024Review
- Metabolic syndrome may be more frequent in treatment-naive sarcoidosis patients.Zeitschrift fur Rheumatologie · 2024Article
- Characteristics and clinical outcomes of patients with sarcoidosis admitted for ST-elevation myocardial infarction in the United States: a propensity matched analysis from the National Inpatient Sample.Archives of medical sciences. Atherosclerotic diseases · 2024Article
- Gut microbiota modulates lung fibrosis severity following acute lung injury in mice.Communications biology · 2022Article
- Comorbidities of sarcoidosis.Annals of medicine · 2022Review
- Clinical phenotyping in sarcoidosis using cluster analysis.Respiratory research · 2022Article
- Risk and predictors of heart failure in sarcoidosis in a population-based cohort study from Sweden.Heart (British Cardiac Society) · 2022Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundSarcoidosis, a systemic disorder characterized by chronic granulomatous inflammation, occurs more frequently among US black women, as do overweight and obesity. Little is known about the relation of overweight and obesity, which induce chronic inflammation, to incidence of sarcoidosis.
methodsWe assessed the relation of obesity and weight gain to the incidence of sarcoidosis in the Black Women's Health Study, a follow-up study of 59,000 US black women aged 21 to 69 years at baseline in 1995. Information on weight at age 18 years, height, current weight, incident sarcoidosis, and covariates was collected at baseline and on biennial follow-up questionnaires. Cox regression models adjusted for age, education, geographic region, smoking, alcohol consumption, and physical activity were used to estimate incidence rate ratios (IRRs) and 95% CIs.
resultsFrom 1995 through 2011, 454 incident cases of sarcoidosis occurred during 707,557 person-years of follow-up. The incidence of sarcoidosis increased with increasing BMI and weight gain. The IRR was 1.40 (95% CI, 0.88-2.25) for BMI ≥ 30 kg/m2 at age 18 years relative to 20 to 24 kg/m2 (P trend = .18), 1.42 (95% CI, 1.07-1.89) for BMI ≥ 35 kg/m2 at baseline relative to 20 to 24 kg/m2 (P trend = .01), and 1.47 (95% CI, 1.10-1.97) for a weight gain between age 18 years and baseline of ≥ 30 kg relative to 0 to 9 kg (P trend = .16). In stratified analyses, there were significant trends of sarcoidosis incidence with increasing BMI and weight gain in women aged ≥ 45 years and ever smokers.
conclusionsThe present study provides evidence that weight gain and obesity during adulthood are associated with increased sarcoidosis incidence.
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