ArticleNanoscale research letters2014
Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.
Article in Nanoscale research letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Calcifying nanoparticles induce apoptosis and calcification in bone marrow mesenchymal stem cellsWorld journal of stem cells · 2025Article
- Calcifying nanoparticles induce cytotoxicity mediated by ROS-JNK signaling pathways.Urolithiasis · 2019Article
- Apoptosis-mediated endothelial toxicity but not direct calcification or functional changes in anti-calcification proteins defines pathogenic effects of calcium phosphate bions.Scientific reports · 2016Article
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7 authors.
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Abstract
We explored the cytotoxic effects of nanobacteria (NB) and nanohydroxyapatites (nHAPs) against human choriocarcinoma cells (JAR) and the mechanisms of action underlying their cytotoxicity. JAR cells were co-cultured with NB and nHAPs for 48 h, and ultrastructural changes were more readily induced by NB than nHAPs. Autophagy in the plasma of JAR cells were observed in the NB group. The rate of apoptosis induced by NB was higher than that for nHAPs. The expression of Bax and FasR proteins in the NB group was stronger than that for the nHAP group. NB probably resulted in autophagic formation. Apoptosis was possibly activated via FasL binding to the FasR signaling pathway.
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