ArticleJournal of veterinary internal medicine2015
Relationship of body size to metabolic markers and left ventricular hypertrophy in cats.
Article in Journal of veterinary internal medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Cardiovascular biomarkers in feline hypertrophic cardiomyopathy phenotype: evidence from the last decade.Veterinary research communications · 2026Pooled it
- Hypertrophic cardiomyopathy in cats: clinical prevalence, risk factors, and outcomes of arterial thromboembolism in a referral population in Tehran, Iran (2020-2024).BMC veterinary research · 2026Article
- Serum Concentrations of Insulin-like Growth Factor-1 (IGF-1), 26S Proteasome (26S PSM), and 3-Methylhistidine (3-MH) in Cats with Hypertrophic Cardiomyopathy.Animals : an open access journal from MDPI · 2025Article
- Natural history of hypertrophic cardiomyopathy in cats from rehoming centers: The CatScan II study.Journal of veterinary internal medicine · 2022Article
- Echocardiographic, morphometric and biomarker changes in female cats followed from 6 to 24 months of life.Journal of feline medicine and surgery · 2021Article
- Association of diet with left ventricular wall thickness, troponin I and IGF-1 in cats with subclinical hypertrophic cardiomyopathy.Journal of veterinary internal medicine · 2020Article
- ACVIM consensus statement guidelines for the classification, diagnosis, and management of cardiomyopathies in cats.Journal of veterinary internal medicine · 2020Article
- Associations among echocardiography, cardiac biomarkers, insulin metabolism, morphology, and inflammation in cats with asymptomatic hypertrophic cardiomyopathy.Journal of veterinary internal medicine · 2020Article
- Diagnostic utility of cardiac troponin I in cats with hypertrophic cardiomyopathy.Journal of veterinary internal medicine · 2018Article
- Human heart failure with preserved ejection versus feline cardiomyopathy: what can we learn from both veterinary and human medicine?Heart failure reviews · 2017Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCats with hypertrophic cardiomyopathy (HCM) are larger and have higher insulin-like growth factor-1 (IGF-1) concentrations than cats without HCM. HYPOTHESIS/
objectivesThe aim of this study was to assess echocardiographic findings in a colony of adult cats to determine the relationship between early growth and left ventricular hypertrophy (LVH). ANIMALS: Twenty-eight neutered adult cats (20 males, 8 females) from a colony ≥ 3 years of age for which growth curves were available.
methodsCase-control study. Physical examination and echocardiography were performed, and body weight, body condition score (BCS), and head length and width were measured. Circulating glucose, insulin, N-terminal pro-B-type natriuretic peptide (NT-proBNP), and IGF-1 concentrations were measured and growth data were collected. Stepwise multivariate analyses were performed.
resultsMean age was 5.2 ± 1.1 years. Current BCSs ranged from 4 to 9 (median, 6) and mean body weight was 4.88 ± 1.29 kg. Variation in body weight was apparent by 6 (mean = 3.26 ± 0.80 kg) and 12 months of age (mean = 4.02 ± 1.02 kg). Cardiac abnormalities included a cardiac murmur (n = 7; 24%), gallop (n = 3; 10%), and arrhythmia (n = 1; 4%). Fourteen of 28 cats (50%) had echocardiographic evidence of LVH. Head width (P = .017), body weight (P < .001), NT-proBNP (P = .023), and IGF-1 (P = .013-.022) were significantly associated with selected measures of LVH. CONCLUSIONS AND CLINICAL IMPORTANCE: Potential associations between body size, IGF-1, LVH, and HCM warrant future prospective studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.