SynthesisJournal of human hypertension2015
Hypertension and risk of depression in the elderly: a meta-analysis of prospective cohort studies.
Synthesis in Journal of human hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 45 citations in OpenAlex.
- Effect of Metabolic Syndrome on Late-Life Depression: Associations with Disease Severity and Treatment Resistance.Journal of the American Geriatrics Society · 2017Trial
- Clinical Associations and Possible Risk Factors for Affective Neuropsychiatric Symptoms in Older Adults With and Without Cognitive Impairment.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026Article
- Comorbidity Between Mood Disorders and Chronic Somatic Diseases, With a Focus on Cardiometabolic Disease, and Its Mechanistic Crosstalk.Depression and anxiety · 2026Review
- U-shaped association between average daily sleep duration and depression among individuals with hypertension: a cross-sectional study based on NHANES 2017-2020.BMC psychiatry · 2025Article
- Exploring the Causal Relationships and Mediating Factors Between Mental Disorders and Hypertension: A Multivariable Mendelian Randomization Study.Global heart · 2025Article
- Exploring the relationship between depression and different multimorbidity patterns among older people covered by long-term care insurance in Shanghai, China.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2022Article
- Longitudinal bidirectional associations between internalizing mental disorders and cardiometabolic disorders in the general adult population.Social psychiatry and psychiatric epidemiology · 2021Article
- Association of Depression with Uncontrolled Hypertension in Primary Care Setting: A Cross-Sectional Study in Less-Developed Northwest China.International journal of hypertension · 2021Article
- Institutional Satisfaction and Anxiety Mediate the Relationship Between Social Support and Depression in Hypertension Patients in Elderly Caring Social Organizations: A Cross-Sectional Study.Frontiers in psychology · 2021Article
- Study protocol: a prospective cohort on non-communicable diseases among primary healthcare users living in Kosovo (KOSCO).BMJ open · 2020Article
- Physical Comorbidity and Health Literacy Mediate the Relationship Between Social Support and Depression Among Patients With Hypertension.Frontiers in public health · 2020Article
- Determining Risk for Depression among Older People Residing in Vietnamese Rural Settings.International journal of environmental research and public health · 2019Article
- Personal, behavioral, and perceived environmental factors associated with late-life depression in older men and women.Psychology research and behavior management · 2019Article
- Comorbidity Status and Annual Total Medical Expenditures in U.S. Hypertensive Adults.American journal of preventive medicine · 2017Article
- The renin-angiotensin system: a possible new target for depression.BMC medicine · 2017Review
- Mental-Physical Comorbidity in Korean Adults: Results from a Nationwide General Population Survey in Korea.Psychiatry investigation · 2016Article
- A community-based controlled trial of a comprehensive psychological intervention for community residents with diabetes or hypertension.Shanghai archives of psychiatry · 2016Article
- Association between anxiety and hypertension: a systematic review and meta-analysis of epidemiological studies.Neuropsychiatric disease and treatment · 2015Article
- Cardiovascular Risk Factors as Differential Predictors of Incident Atypical and Typical Major Depressive Disorder in US Adults.Psychosomatic medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of the study was to assess the relationship between hypertension and risk of depression. The relationship between hypertension and depression has been discussed for a long time, but the results are controversial. Studies were searched from PubMed and Cochrane up to 24 March 2014. Any prospective cohort study, which possibly reported the relationship between hypertension and depression, was included. The random effect model was used to calculate the pooled relative risk (RR). Finally, five prospective cohort studies were included for analysis, with a total of 9647 participants involved. Our meta-analysis does not support that hypertension is probably a risk factor of depression. The pooled RR was 1.16 (95% confidence interval: 0.91, 1.42) when those exposed to hypertension were compared with those who were not. Subgroup analysis, sensitivity analysis and publication bias test suggested that the overall result of this analysis was robust. Further studies are needed to exclude the effects of other confounding factors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.