Evidence map›Paper›PMID 25410893›Full record

ArticlePharmacogenomics2014

Pilot study of pharmacist-assisted delivery of pharmacogenetic testing in a primary care setting.

Susanne B Haga, Nancy M Allen LaPointe, Alex Cho, Shelby D Reed, Rachel Mills, Jivan Moaddeb, Geoffrey S Ginsburg

Registry-linked trialAbstract read
In one paragraph

Article in Pharmacogenomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03257605 (Implementation of a Pharmacist-Led Pharmacogenomics Service for the Program of All-inclusive Care for the Elderly), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03257605 completednot on this map

Implementation of a Pharmacist-Led Pharmacogenomics Service for the Program of All-inclusive Care for the Elderly (PHARM-GENOME-PACE)

TypeobservationalSponsorTabula Rasa HealthCareRan2014 to 2017Enrolled296ConditionsPharmacogenomics, Medication Therapy Management
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  13. Pharmacists should jump onto the clinical pharmacogenetics train.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2016
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Susanne B HagaDuke University Center for Applied Genomics & Precision Medicine, 304 Research Drive, Box 90141 Durham, NC 27708, USA.
Nancy M Allen LaPointe
Alex Cho
Shelby D Reed
Rachel Mills
Jivan Moaddeb
Geoffrey S Ginsburg

Funding

Pharmacogenetic Testing: Challenges of Clinical IntegrationR01GM081416 · NIGMS · DUKE UNIVERSITY · PI HAGA, SUSANNE · 2008 to 2018
$4.6M
NIGMS NIH HHS R01 GM081416NIGMS NIH HHS R01-GM081416
6 · The paper itself

Abstract

aimTo describe the rationale and design of a pilot program to implement and evaluate pharmacogenetic (PGx) testing in a primary care setting. STUDY RATIONALE: Several factors have impeded the uptake of PGx testing, including lack of provider knowledge and challenges with operationalizing PGx testing in a clinical practice setting. STUDY

designWe plan to compare two strategies for the implementation of PGx testing: a pharmacist-initiated testing arm compared with a physician-initiated PGx testing arm. Providers in both groups will be required to attend an introduction to PGx seminar. Anticipated results: We anticipate that providers in the pharmacist-initiated group will be more likely to order PGx testing than providers in the physician-initiated group.

conclusionOverall, we aim to generate data that will inform an effective delivery model for PGx testing and to facilitate a seamless integration of PGx testing in primary care practices.

Indexed as

PharmacistsPharmacogeneticsPrimary Health CareAgedFemaleHumansMaleMiddle AgedPilot Projectsclinical utilitypharmacist supportpharmacogeneticspharmacogenetic testingprimary care

Identifiers

PMID25410893
PMCPMC4280849

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.