ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2015
Single low-dose CT scan optimized for rest-stress PET attenuation correction and quantification of coronary artery calcium.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Radiopharmaceuticals for PET and SPECT Imaging: A Literature Review over the Last Decade.International journal of molecular sciences · 2022Pooled it
- The prognostic value of visual and automatic coronary calcium scoring from low-dose computed tomography-[15O]-water positron emission tomography.European heart journal. Cardiovascular Imaging · 2024Article
- Comparison of the prognostic value between quantification and visual estimation of coronary calcification from attenuation CT in patients undergoing SPECT myocardial perfusion imaging.The international journal of cardiovascular imaging · 2024Article
- The impact of coronary calcium score as an addition to myocardial perfusion imaging in altering clinical management (ICCAMPA trial).Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Automated cardiovascular risk categorization through AI-driven coronary calcium quantification in cardiac PET acquired attenuation correction CT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Integration of coronary artery calcium scoring from CT attenuation scans by machine learning improves prediction of adverse cardiovascular events in patients undergoing SPECT/CT myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Performance of visual, manual, and automatic coronary calcium scoring of cardiacJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- PET-derived bone information from 18F-sodium fluoride: A perfect match for whole-body PET/MR attenuation correction?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Best practice for the nuclear medicine technologist in CT-based attenuation correction and calcium score for nuclear cardiology.European journal of hybrid imaging · 2020Review
- Automated calcium scores collected during myocardial perfusion imaging improve identification of obstructive coronary artery disease.International journal of cardiology. Heart & vasculature · 2020Article
- Leveraging latest computer science tools to advance nuclear cardiology.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Clinical performance of Rb-82 myocardial perfusion PET and Tc-99m-based SPECT in patients with extreme obesity.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Automatic determination of cardiovascular risk by CT attenuation correction maps in Rb-82 PET/CT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Coronary calcium scoring of CT attenuation correction scans: Automatic, manual, or visual?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Combined evaluation of regional coronary artery calcium and myocardial perfusion byEuropean journal of nuclear medicine and molecular imaging · 2018Article
- Article
- Extending the Use of Coronary Calcium Scanning to Clinical Rather Than Just Screening Populations: Ready for Prime Time?Circulation. Cardiovascular imaging · 2016Article
- Review of cardiovascular imaging in the journal of nuclear cardiology in 2015. Part 1 of 2: Plaque imaging, positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Review
- Quantitative Coronary Physiology for Clinical Management: the Imaging Standard.Current cardiology reports · 2016Review
- Low-dose CT-derived attenuation scan: One acquisition, more applications?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
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Funding
Abstract
backgroundCoronary artery calcium is an important marker of coronary artery disease. Myocardial perfusion imaging (MPI) using PET-CT technology requires a CT scan for attenuation correction (CTAC) but is not used routinely to measure coronary calcium burden. This study aimed to determine if a low-dose CTAC scan can also accurately quantify coronary artery calcium.
methodsTwenty-three patients underwent both a traditional coronary artery calcium scan on a dedicated cardiac CT scanner (CAC-CT) and a myocardial perfusion scan on a hybrid PET-CT scanner. The standard MPI protocol includes rest and stress-matched PET and CTAC scans. The post-stress CTAC scan was modified to approximate the CAC-CT scan protocol while maintaining ~0.5 mSv dose. Coronary artery calcium scores were compared between the Ca-CTAC and CAC-CT scans.
resultsThe modified Ca-CTAC scan showed a trend toward slight decreases in segmental stress perfusion of 2-3.5% in the anterior wall segments (P < 0.05). Correlation and agreement between the proposed Ca-CTAC and standard CAC-CT calcium scores at the optimal threshold of 110 HU were also excellent (r (2) = 0.99, κ = 1.0). There was a small difference in the regression slope vs unity: Ca-CTAC = 0.96 × CAC (P < 0.05), but the categorical classification of calcium was accurate in all twenty-three patients (κ = 1.0).
conclusionA single low-dose rest CTAC scan can be used for accurate attenuation correction of rest and stress PET perfusion images, thus allowing a post-stress CTAC scan to be optimized for improved quantification of coronary artery calcium without increasing radiation dose vs standard protocols.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.