ReviewThe British journal of radiology2015
A review of performance of near-infrared fluorescence imaging devices used in clinical studies.
Review in The British journal of radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
84 citing papers in PubMed, 2 syntheses or guidelines pooled it, 175 citations in OpenAlex.
- Indocyanine Green in Bariatric Surgery: a Systematic Review.Obesity surgery · 2023Pooled it
- Optimizing the image of fluorescence cholangiography using ICG: a systematic review and ex vivo experiments.Surgical endoscopy · 2018Pooled it
- Fluorescent Labeling Strategies for Tracking Micro- and Nanoplastics in Biological Systems.Materials (Basel, Switzerland) · 2026Review
- Translational Nanomedicine and Delivery Tools for Cardiovascular Disease Therapy and Diagnostics.Advances in experimental medicine and biology · 2026Review
- Optomechanical Properties of Swine Skin Tissue Treated With a Nontoxic Optical Clearing Agent.Journal of biophotonics · 2025Article
- Imaging and management of lymphedema in the era of precision oncology.The British journal of radiology · 2025Review
- Bright and Specific Targeting of Metastatic Lymph Nodes in Orthotopic Mouse Models of Gastric Cancer with a Fluorescent Anti-CEA Antibody.Annals of surgical oncology · 2025Article
- Fluorescence Lifetime Endoscopy with a Nanosecond Time-Gated CAPS Camera with IRF-Free Deep Learning Method.Sensors (Basel, Switzerland) · 2025Article
- Optical molecular imaging technology and its application in precise surgical navigation of liver cancer.Theranostics · 2025Review
- Impact of signal-to-noise ratio and contrast definition on the sensitivity assessment and benchmarking of fluorescence molecular imaging systems.Journal of biomedical optics · 2025Article
- Non-invasive early-stage cancer detection: current methods and future perspectives.Clinical and experimental medicine · 2024Review
- Review
- State of the art medical devices for fluorescence-guided surgery (FGS): technical review and future developments.Surgical endoscopy · 2024Review
- Developments in the Use of Indocyanine Green (ICG) Fluorescence in Colorectal Surgery.Journal of clinical medicine · 2024Review
- Convolutional neural network advances in demosaicing for fluorescent cancer imaging with color-near-infrared sensors.Journal of biomedical optics · 2024Article
- A Review of Image Sensors Used in Near-Infrared and Shortwave Infrared Fluorescence Imaging.Sensors (Basel, Switzerland) · 2024Review
- eTFC-01: a dual-labeled chelate-bridged tracer for SSTR2-positive tumors.EJNMMI radiopharmacy and chemistry · 2024Article
- Deep learning-based label-free imaging of lymphatics and aqueous veins in the eye using optical coherence tomography.Scientific reports · 2024Article
- Multicolor fluorescence microscopy for surgical guidance using a chip-scale imager with a low-NA fiber optic plate and a multi-bandpass interference filter.Biomedical optics express · 2024Article
- Current and Developing Lymphatic Imaging Approaches for Elucidation of Functional Mechanisms and Disease Progression.Molecular imaging and biology · 2024Review
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Near-infrared fluorescence (NIRF) molecular imaging holds great promise as a new "point-of-care" medical imaging modality that can potentially provide the sensitivity of nuclear medicine techniques, but without the radioactivity that can otherwise place limitations of usage. Recently, NIRF imaging devices of a variety of designs have emerged in the market and in investigational clinical studies using indocyanine green (ICG) as a non-targeting NIRF contrast agent to demark the blood and lymphatic vasculatures both non-invasively and intraoperatively. Approved in the USA since 1956 for intravenous administration, ICG has been more recently used off label in intradermal or subcutaneous administrations for fluorescence imaging of the lymphatic vasculature and lymph nodes. Herein, we summarize the devices of a variety of designs, summarize their performance in lymphatic imaging in a tabular format and comment on necessary efforts to develop standards for device performance to compare and use these emerging devices in future, NIRF molecular imaging studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.