ReviewHead and neck pathology2014
Metastatic tumors to the jaws and mouth.
Review in Head and neck pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed, 1 synthesis or guideline pooled it, 200 citations in OpenAlex.
- Follicular thyroid carcinoma metastasis to the facial skeleton: a systematic review.BMC cancer · 2017Pooled it
- Metastatic Cancers to the Oral Cavity: A 42-Year Experience.Head and neck pathology · 2026Article
- A Rare Oral Metastatic Lesion as the Initial Diagnosis of Small Cell Lung Cancer: Case Report and Systematic Review.Journal of clinical medicine · 2026Review
- Synchronous Haemorrhagic Tumors of the Anterior Maxilla and Oropharynx.Clinical case reports · 2026Article
- Metastatic Lung Carcinoma Presenting as Pyogenic Granuloma Around Dental Implant.Clinical case reports · 2026Article
- Inflammaging in periodontal, periapical, and malignancy-associated disease: drivers of alveolar bone loss and repair.Journal of bone and mineral metabolism · 2026Review
- Rare mandibular metastasis of neuroblastoma in a child: a case report.Frontiers in dental medicine · 2026Article
- Oral metastasis of primary testicular choriocarcinoma: A case report and brief review of the literature.Journal of clinical and experimental dentistry · 2025Review
- Oral Metastasis as a Harbinger of Terminal Lung Adenocarcinoma: A Case Study of Rare and Rapid Decline.Cureus · 2025Article
- Metastatic SMARCA4-Deficient Undifferentiated Carcinoma of the Oral Cavity: A Case Report and Review of Literature.Head and neck pathology · 2025Review
- Oral Soft Tissue and Jawbone Sarcomas: A Retrospective Clinicopathologic Analysis of 128 Cases from Two Institutions and Comprehensive Literature Review.Head and neck pathology · 2025Review
- Treatment strategy for maxillary gingival metastasis arising from gastric adenocarcinoma: A case report and literature review.Molecular and clinical oncology · 2025Article
- Article
- Pattern and Outcome of Metastatic Malignant Lesions to the Jaws: A Systematic Review of 594 Cases.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Oral Metastasis From Colorectal Adenocarcinoma: Report of a New Case and a Scoping Review.Case reports in dentistry · 2025Article
- Tumor Metastasis to the Oral Soft Tissues and Jaw Bones: A Retrospective Study and Review of the Literature.Clinical and experimental dental research · 2024Review
- Advances in Raman spectroscopy for characterising oral cancer and oral potentially malignant disorders.Expert reviews in molecular medicine · 2024Review
- Article
- Renal Cell Carcinoma Metastasizing to Oral Soft Tissues: Systematic Review.Avicenna journal of medicine · 2024Review
- Metastatic gallbladder cancer presenting as numb chin syndrome: A case report and literature review.Biomedical reports · 2024Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metastatic dissemination to the oral cavity is rare and is usually the evidence of a wide spread disease with an average survival rate of 7 months. In almost a quarter of the cases, oral metastasis was found to be the first indication of an occult malignancy at a distant site. Metastatic lesions can be found anywhere in the oral cavity, however, the jaw bones with the molar area is the most frequently involved site. In the oral soft tissues, the gingiva is the most common site, suggesting the possible role of inflammation in the attraction of metastatic deposits. The most common primary malignancies presenting oral metastases were the lung, kidney, liver, and prostate for men, and breast, female genital organs, kidney, and colo-rectum for women. Most patients with jawbone metastasis complain of swelling, pain, and paresthesia. An exophytic lesion is the most common clinical presentation of metastatic lesions in the oral soft tissues. Early lesions, mainly those located in the gingiva, may resemble a hyperplastic or reactive lesion. Once a lesion is recognized as metastasis, the primary tumor site should be identified following clinical, radiological and histopathological investigations. If standardized diagnostic workup fails to detect the site of origin, then the term carcinoma of unknown primary is applied. Personalized medicine tools such as tissue-of-origin assays should be applied, either by immunohistochemical testing or by molecular-profiling methods as these may lead to a more favorable outcome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.