ArticlePloS one2014
Genome-wide investigation and expression profiling of AP2/ERF transcription factor superfamily in foxtail millet (Setaria italica L.).
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.
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86 citing papers in PubMed, 194 citations in OpenAlex.
- Genome-wide identification and evolutionary analysis of the ERF-VII gene family in the tea plant (Camellia sinensis) and functional characterization of CsRAP2.2 in response to cold stress.Plant cell reports · 2026Article
- Harnessing genomics and transcriptomics to explore the genetic and molecular basis of abiotic stress tolerance in minor millets - a comprehensive review.Functional & integrative genomics · 2026Review
- Abiotic Stress Tolerance in Foxtail Millet (Plants (Basel, Switzerland) · 2026Review
- Transcriptomic Profiling Across Developmental Stages ofMetabolites · 2026Article
- Comprehensive characterization of the genes in AP2/ERF family and their involvement in salt-alkali stress response duringFrontiers in plant science · 2026Article
- Integrating ATAC-Seq and Pan-Genomics Identifies Stress-MemoryFood science & nutrition · 2025Article
- Mechanisms of Salt and Drought Stress Responses in Foxtail Millet.Plants (Basel, Switzerland) · 2025Review
- Genome-wide identification and expression analysis of the DREB gene family in foxtail millet (Setaria Italica L.).BMC plant biology · 2025Article
- Transcriptome Analysis Reveals the Pivotal Genes and Regulation Pathways Under Cold Stress and IdentifiesPlants (Basel, Switzerland) · 2025Article
- Review
- Comparative transcriptome and coexpression network analysis reveals key pathways and hub candidate genes associated with sunflower (Helianthus annuus L.) drought tolerance.BMC plant biology · 2024Article
- Genome-wide identification and expression profiling of the ABI5 gene family in foxtail millet (Setaria italica).BMC plant biology · 2024Article
- Genome-Wide Identification and Transcriptional Analysis ofInternational journal of molecular sciences · 2024Article
- Transcriptome Profiles RevealsPlants (Basel, Switzerland) · 2024Article
- Genome-wide characterization and evolutionary analysis of the AP2/ERF gene family in lettuce (Lactuca sativa).Scientific reports · 2023Article
- Review
- Article
- Comprehensive and evolutionary analysis ofFrontiers in plant science · 2023Article
- Genome-Wide Analysis of AP2/ERF Gene Superfamily in Ramie (International journal of molecular sciences · 2022Article
- Genome-wide identification, molecular evolution and expression analysis of the non-specific lipid transfer protein (nsLTP) family in Setaria italica.BMC plant biology · 2022Article
26 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The APETALA2/ethylene-responsive element binding factor (AP2/ERF) family is one of the largest transcription factor (TF) families in plants that includes four major sub-families, namely AP2, DREB (dehydration responsive element binding), ERF (ethylene responsive factors) and RAV (Related to ABI3/VP). AP2/ERFs are known to play significant roles in various plant processes including growth and development and biotic and abiotic stress responses. Considering this, a comprehensive genome-wide study was conducted in foxtail millet (Setaria italica L.). A total of 171 AP2/ERF genes were identified by systematic sequence analysis and were physically mapped onto nine chromosomes. Phylogenetic analysis grouped AP2/ERF genes into six classes (I to VI). Duplication analysis revealed that 12 (∼7%) SiAP2/ERF genes were tandem repeated and 22 (∼13%) were segmentally duplicated. Comparative physical mapping between foxtail millet AP2/ERF genes and its orthologs of sorghum (18 genes), maize (14 genes), rice (9 genes) and Brachypodium (6 genes) showed the evolutionary insights of AP2/ERF gene family and also the decrease in orthology with increase in phylogenetic distance. The evolutionary significance in terms of gene-duplication and divergence was analyzed by estimating synonymous and non-synonymous substitution rates. Expression profiling of candidate AP2/ERF genes against drought, salt and phytohormones revealed insights into their precise and/or overlapping expression patterns which could be responsible for their functional divergence in foxtail millet. The study showed that the genes SiAP2/ERF-069, SiAP2/ERF-103 and SiAP2/ERF-120 may be considered as potential candidate genes for further functional validation as well for utilization in crop improvement programs for stress resistance since these genes were up-regulated under drought and salinity stresses in ABA dependent manner. Altogether the present study provides new insights into evolution, divergence and systematic functional analysis of AP2/ERF gene family at genome level in foxtail millet which may be utilized for improving stress adaptation and tolerance in millets, cereals and bioenergy grasses.
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