Evidence map›Paper›PMID 25409106›Full record

ArticleSleep2015

Racial/Ethnic Differences in Sleep Disturbances: The Multi-Ethnic Study of Atherosclerosis (MESA).

Xiaoli Chen, Rui Wang, Phyllis Zee, Pamela L Lutsey, Sogol Javaheri, Carmela Alcántara, Chandra L Jackson, Michelle A Williams, Susan Redline

Registry-linked trialOpen access · bronzeAbstract readComparative Study
In one paragraph

Article in Sleep, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03901534 (Assessment of Continuous Positive Airway Pressure Therapy in OSA and ILD), which is not on this map. Cited by 598 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
598citing papers in PubMed, 2 pooled it
25.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03901534 naterminatednot on this mapstarted 2023, after this paper: background citation

Assessment of Continuous Positive Airway Pressure Therapy in OSA and ILD

TypeinterventionalSponsorColumbia UniversityRan2023 to 2023Enrolled2,021ConditionsInterstitial Lung Disease, Obstructive Sleep ApneaArmsContinuous positive airway pressure (CPAP) therapy, Nox A1 Recorder
3 · Its place in the literature

Who cites it

598 citing papers in PubMed, 2 syntheses or guidelines pooled it, 890 citations in OpenAlex.

  1. Pooled it
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  8. Association of vitamin D and B12 levels with actigraphic sleep in cognitively unimpaired middle-aged and older adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
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538 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Xiaoli ChenDepartment of Epidemiology, Harvard School of Public Health, Boston, MA.
Rui WangDepartment of Medicine, Harvard Medical School; Brigham and Women's Hospital and Beth Israel Deaconess Medical School, Boston, MA.
Phyllis ZeeDepartment of Neurobiology, Northwestern University School of Medicine, Chicago, IL.
Pamela L LutseyDivision of Epidemiology and Community Health, University of Minnesota, Minnesota, Minneapolis, MN.
Sogol JavaheriDepartment of Medicine, Harvard Medical School; Brigham and Women's Hospital and Beth Israel Deaconess Medical School, Boston, MA.
Carmela AlcántaraCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY.
Chandra L JacksonDepartment of Nutrition, Harvard School of Public Health, Boston, MA.
Michelle A WilliamsDepartment of Epidemiology, Harvard School of Public Health, Boston, MA.
Susan RedlineDepartment of Medicine, Harvard Medical School; Brigham and Women's Hospital and Beth Israel Deaconess Medical School, Boston, MA.
Harvard University · USBeth Israel Deaconess Medical Center · USColumbia University Irving Medical Center · USNorthwestern University · USUniversity of Minnesota · US

Funding

Harvard Clinical and Translational Science Center (UL1)UL1TR000170 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2012 to 2013
$31.4M
ASSOCIATION OF SLEEP DISORDERS WITH CARDIOVASCULAR HEALTH ACROSS ETHNIC GROUPSR01HL098433 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI REDLINE, SUSAN S. · 2010 to 2015
$8.2M
Leveraging Family Data to Identify Genetic Variants for Sleep ApneaR01HL113338 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LIN, XIHONG, REDLINE, SUSAN S. · 2012 to 2016
$4.4M
Elucidation of the Influence of Sleep Apnea on Risk of Atrial FibrillationR01HL109493 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI MEHRA, REENA · 2011 to 2015
$3.7M
Sleep-Disordered Breathing and Risk for CVD and Stroke in the Jackson Heart StudyR01HL110068 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI REDLINE, SUSAN S., WILSON, JAMES GRAHAM · 2012 to 2015
$2.9M
A Planning Study: Sleep Apnea Intervention for Cardiovascular Disease ReductionU34HL105277 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MITTLEMAN, MURRAY A, REDLINE, SUSAN S. · 2010 to 2012
$2.5M
Ecological Link of Psychosocial Stress to Exercise: Personalized PathwaysR01HL115941 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BURG, MATTHEW M, DAVIDSON, KARINA W. · 2012 to 2014
$1.7M
Prevention and Risk Identification of SUDEP Mortality - the PRISM ProjectP20NS076965 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI LHATOO, SAMDEN · 2011 to 2013
$1.4M
Sleep-Related Respiratory and Electrophysiological Atrial Fibrillation Predictor R21HL108226 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI MEHRA, REENA · 2012 to 2013
$515k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--EBCT READINGN01HC095169 · HC · LA BIOMED RES INST/ HARBOR UCLA MED CTR · PI DETRANO, ROBERT · 1999 to 2001
$124k
NCATS NIH HHS 8UL1TR000170-07NCATS NIH HHS UL1 TR000170NHLBI NIH HHS 1R01HL083075-01NHLBI NIH HHS 1R01HL110068-01A1NHLBI NIH HHS 1R01HL113338-01NHLBI NIH HHS 1U34HL105277-01NHLBI NIH HHS 3R01HL115941-01S1NHLBI NIH HHS N01-HC-95169NHLBI NIH HHS R01 HL098433NHLBI NIH HHS R01HL098433NHLBI NIH HHS R01 HL098433-02S1NHLBI NIH HHS R01 HL109493NHLBI NIH HHS R21 HL108226NINDS NIH HHS P20NS076965
6 · The paper itself

Abstract

objectivesThere is limited research on racial/ethnic variation in sleep disturbances. This study aimed to quantify the distributions of objectively measured sleep disordered breathing (SDB), short sleep duration, poor sleep quality, and self-reported sleep disturbances (e.g., insomnia) across racial/ethnic groups.

designCross-sectional study.

settingSix US communities.

participantsRacially/ethnically diverse men and women aged 54-93 y in the Multi-Ethnic Study of Atherosclerosis Sleep Cohort (n = 2,230).

interventionsN/A. MEASUREMENTS AND

resultsInformation from polysomnography-measured SDB, actigraphy-measured sleep duration and quality, and self-reported daytime sleepiness were obtained between 2010 and 2013. Overall, 15.0% of individuals had severe SDB (apnea-hypopnea index [AHI] ≥ 30); 30.9% short sleep duration (< 6 h); 6.5% poor sleep quality (sleep efficiency < 85%); and 13.9% had daytime sleepiness. Compared with Whites, Blacks had higher odds of sleep apnea syndrome (AHI ≥ 5 plus sleepiness) (sex-, age-, and study site-adjusted odds ratio [OR] = 1.78, 95% confidence interval [CI]: 1.20, 2.63), short sleep (OR = 4.95, 95% CI: 3.56, 6.90), poor sleep quality (OR = 1.57, 95% CI: 1.00, 2.48), and daytime sleepiness (OR = 1.89, 95% CI: 1.38, 2.60). Hispanics and Chinese had higher odds of SDB and short sleep than Whites. Among non-obese individuals, Chinese had the highest odds of SDB compared to Whites. Only 7.4% to 16.2% of individuals with an AHI ≥ 15 reported a prior diagnosis of sleep apnea.

conclusionsSleep disturbances are prevalent among middle-aged and older adults, and vary by race/ethnicity, sex, and obesity status. The high prevalence of sleep disturbances and undiagnosed sleep apnea among racial/ethnic minorities may contribute to health disparities.

Indexed as

AtherosclerosisActigraphyAgedAged, 80 and overAsian PeopleCohort StudiesCross-Sectional StudiesEthnicityFemaleHispanic or LatinoHumansMaleMiddle AgedObesityOdds RatioPolysomnographyapnea-hypopnea indexbody mass indexdaytime sleepinessobesitypolysomnographyrace/ethnicitysleep disordered breathingsleep disturbancesleep durationsleep quality

Identifiers

PMID25409106
PMCPMC4434554
OpenAlexW1937674079

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.