Evidence map›Paper›PMID 25408859›Full record

ReviewMediterranean journal of hematology and infectious diseases2014

Diagnosis and subclassification of acute lymphoblastic leukemia.

Sabina Chiaretti, Gina Zini, Renato Bassan

Registry-linked trialAbstract readReview
In one paragraph

Review in Mediterranean journal of hematology and infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04092348 (Value of FoxO3a and PU.1 Expression in Pediatric Acute Lymphoblastic Leukemia), which is not on this map. Cited by 93 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04092348 unknown statusnot on this mapstarted 2023, after this paper: background citation

Value of FoxO3a and PU.1 Expression in Pediatric Acute Lymphoblastic Leukemia

TypeobservationalSponsorAssiut UniversityRan2023 to 2024Enrolled53ConditionsAcute Lymphoblastic LeukemiaArmscomplete blood count
3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Diagnostic Concordance and Superiority of Flow Cytometry Over Immunohistochemistry in Acute Leukemia Immunophenotyping: A Single-Center Study.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Metabolites · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Novel Therapeutic Approaches in Pediatric Acute Lymphoblastic Leukemia.International journal of molecular sciences · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Report of Granular Blasts in Adult B-Cell ALL: A Rare Morphological Mimic of AML.International journal of hematology-oncology and stem cell research · 2025
    Article
  18. Review
  19. Review
  20. Article

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sabina ChiarettiDivision of Hematology, Department of Cellular Biotechnologies and Hematology, "Sapienza" University of Rome, Rome, Italy.
Gina ZiniHematology, Catholic University Sacred Heart Policlinico Gemelli, Rome, Italy.
Renato BassanHematology and Bone Marrow Transplant Unit, Ospedale dell'Angelo e SS. Giovanni e Paolo, Mestre-Venezia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute lymphoblastic leukemia (ALL) is a disseminated malignancy of B- or T-lymphoblasts which imposes a rapid and accurate diagnostic process to support an optimal risk-oriented therapy and thus increase the curability rate. The need for a precise diagnostic algorithm is underlined by the awareness that both ALL therapy and related success rates may vary greatly between ALL subsets, from standard chemotherapy in patients with standard-risk ALL, to allotransplantation (SCT) and targeted therapy in high-risk patients and cases expressing suitable biological targets, respectively. This review summarizes how best to identify ALL and the most relevant ALL subsets.

Identifiers

PMID25408859
PMCPMC4235437

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.