ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada2014
Bone mineral density status in urolithiasis patients with vitamin D inadequacy followed at a tertiary stone centre.
Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Comparison of the bone mineral density status of patients with kidney stones stratified by stone composition.World journal of urology · 2024Article
- Analysis of vitamin D deficiency in calcium stone-forming patients.International urology and nephrology · 2016Article
- Leisure time physical activity, smoking and risk of recent symptomatic urolithiasis: Survey of stone clinic patients.Canadian Urological Association journal = Journal de l'Association des urologues du CanadaArticle
- Combined vitamin D and calcium supplementation in vitamin D inadequate patients with urolithiasis: Impact on hypercalciuria and de novo stone formation.Canadian Urological Association journal = Journal de l'Association des urologues du CanadaArticle
- CUA guideline on the evaluation and medical management of the kidney stone patient - 2016 update.Canadian Urological Association journal = Journal de l'Association des urologues du CanadaArticle
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4 authors.
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Abstract
introductionWe assessed abnormalities in bone mineral density (BMD) and the risk of hip and major osteoporotic fractures in urolithiasis patients with vitamin D inadequacy (VDI) followed at a tertiary stone centre.
methodsStone-free patients with VDI were invited to undergo dual-energy x-ray absorptiometry (DXA) scans to assess for BMD abnormalities at the femoral neck and lumbar spine. The World Health Organization's validated Fracture Risk Assessment Tool (FRAX) was used to calculate the risk of hip and major osteoporotic fractures within 10 years. Patients with primary hyperparathyroidism or hypercalcemia were excluded.
resultsIn total, 50 consecutive patients were included between June 2011 and August 2012, including 26 (52%) males. The median age was 51 years and the median 25-hydroxyl vitamin D (25[OH] D) was 18.8 ng/mL. Thirty patients (60%) had abnormal T-scores on DXA studies. This decreased to 22 (44%) when age-matched Z-scores were used; 36% had osteopenia and 8% had osteoporosis. Femoral neck and lumbar spines were affected in 24% and 32% of patients, respectively. Recurrent stone-formers had significantly lower BMD when compared with first-time stone formers. Median serum 25(OH)D was comparable between patients with normal and abnormal DXA scans (18.6 vs. 18.8 ng/mL; p = 0.91). Five patients (10%) were at high risk (≥3%) of hip fractures within 10 years.
conclusionA high prevalence of abnormal DXA scans was found in urolithiasis patients with VDI, including 5 patients (10%) at high risk of hip fractures. Future studies need to assess the economic impact of obtaining DXA scans on urolithiasis patients with VDI, especially in recurrent stone-formers.
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