ReviewJournal of Korean medical science2014
Diagnostic and therapeutic approach for acute paraquat intoxication.
Review in Journal of Korean medical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.
- Sequential organ failure assessment in predicting mortality after paraquat poisoning: A meta-analysis.PloS one · 2018Pooled it
- A rare intravenous paraquat exposure presenting with novel and atypical severe clinical manifestations.Indian journal of pharmacology · 2026Article
- Favorable outcome in paraquat poisoning with acute kidney injury in a resource-limited setting: a case report.Annals of medicine and surgery (2012) · 2026Article
- Indian Society of Critical Care Medicine Position Statement on the Management of Paraquat Poisoning.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Urine Dithionite-guided Hemoperfusion in Acute Paraquat Poisoning: A Retrospective Observational Study from South India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Antioxidative Effects of Crocin-loaded Noisome in Paraquat-induced Oxidative Stress in Lung Rat.Cell biochemistry and biophysics · 2025Article
- Successful management of paraquat poisoning: a case report.Journal of medical case reports · 2025Article
- Proteomic characterization of molecular mechanisms of paraquat-induced lung injury in a mouse model.Respiratory research · 2025Article
- Spectrophotometric analysis of purple urine secondary to methylene blue and hydroxocobalamin co-administration.Journal of nephrology · 2024Article
- Review
- Predicting mortality in paraquat poisoning through clinical findings, with a focus on pulmonary and cardiovascular system disorders.Journal of pharmaceutical policy and practice · 2023Article
- Remarkable Recovery in a Patient with Lethal Dose Paraquat Poisoning: A Case Report.JNMA; journal of the Nepal Medical Association · 2023Article
- Current situation and influencing factors for suicidal intent in patients with intentional acute pesticide poisoning.Frontiers in public health · 2023Article
- Sociodemographic and clinical characteristics related to the final condition of patients intoxicated by paraquat in a hospital in southwestern ColombiaBiomedica : revista del Instituto Nacional de Salud · 2022Observational
- Risk factors and optimal predictive scoring system of mortality for children with acute paraquat poisoning.World journal of clinical cases · 2022Article
- Wnt-induced secreted proteins-1 play an important role in paraquat-induced pulmonary fibrosis.BMC pharmacology & toxicology · 2022Article
- The efficacy of hemodialysis on paraquat poisoning mortality: A systematic review and meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022Review
- Oxaloacetate acid ameliorates paraquat-induced acute lung injury by alleviating oxidative stress and mitochondrial dysfunction.Frontiers in pharmacology · 2022Article
- Thoracic radiographic features of fatal paraquat intoxication in eleven dogs.The veterinary quarterly · 2021Article
- Endoplasmic reticulum stress promotes epithelial‑mesenchymal transition via the PERK signaling pathway in paraquat‑induced pulmonary fibrosis.Molecular medicine reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paraquat (PQ) has known negative human health effects, but continues to be commonly used worldwide as a herbicide. Our clinical data shows that the main prognostic factor is the time required to achieve a negative urine dithionite test. Patient survival is a 100% when the area affected by ground glass opacity is <20% of the total lung volume on high-resolution computed tomography imaging 7 days post-PQ ingestion. The incidence of acute kidney injury is approximately 50%. The average serum creatinine level reaches its peak around 5 days post-ingestion, and usually normalizes within 3 weeks. We obtain two connecting lines from the highest PQ level for the survivors and the lowest PQ level among the non-survivors at a given time. Patients with a PQ level between these two lines are considered treatable. The following treatment modalities are recommended to preserve kidney function: 1) extracorporeal elimination, 2) intravenous antioxidant administration, 3) diuresis with a fluid, and 4) cytotoxic drugs. In conclusion, this review provides a general overview on the diagnostic procedure and treatment modality of acute PQ intoxication, while focusing on our clinical experience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.